Yui Mano
Tohoku University
14 Papers
106 Citations
Yui Mano is an academic researcher from Tohoku University. The author has contributed to research in topics: Glioma & Medicine. The author has an hindex of 6, co-authored 13 publications. Previous affiliations of Yui Mano include Kitasato University.
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Papers
Convection-enhanced delivery of SN-38-loaded polymeric micelles (NK012) enables consistent distribution of SN-38 and is effective against rodent intracranial brain tumor models.
Rong Zhang,Ryuta Saito,Yui Mano,Akira Sumiyoshi,Masayuki Kanamori,Yukihiko Sonoda,Ryuta Kawashima,Teiji Tominaga +7 more
TL;DR: Convection-enhanced delivery of NK012, a novel SN-38-loaded polymeric micelle, represents an effective treatment option for malignant gliomas and has potential for clinical application.
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Intraparenchymal ultrasound application and improved distribution of infusate with convection-enhanced delivery in rodent and nonhuman primate brain
Yui Mano,Ryuta Saito,Yoichi Haga,Tadao Matsunaga,Rong Zhang,Masashi Chonan,Shinya Haryu,Takuhiro Shoji,Aya Sato,Yukihiko Sonoda,Noriko Tsuruoka,Keisuke Nishiyachi,Akira Sumiyoshi,Hiroi Nonaka,Ryuta Kawashima,Teiji Tominaga +15 more
TL;DR: The UFD system facilitated the distribution of EBD and Gd-DTPA more effectively than conventional CED and may provide a new treatment approach for CNS disorders.
Dynamic changes in magnetic resonance imaging appearance of dysembryoplastic neuroepithelial tumor with or without malignant transformation
Yui Mano,Toshihiro Kumabe,Ichiyo Shibahara,Ryuta Saito,Yukihiko Sonoda,Mika Watanabe,Teiji Tominaga +6 more
TL;DR: The authors report 2 unusual cases of DNET: an enlarging lesion that developed an enhancing component over the natural course of 4 years, and a recurrent DNET that developed a enhancing component 10-11 years after gross-total resection.
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Concentration rather than dose defines the local brain toxicity of agents that are effectively distributed by convection-enhanced delivery
Rong Zhang,Ryuta Saito,Yui Mano,Masayuki Kanamori,Yukihiko Sonoda,Toshihiro Kumabe,Teiji Tominaga +6 more
TL;DR: Convection-enhanced delivery as a potentially effective drug-delivery strategy into the central nervous system may be more important for the toxicity of agents that are effectively distributed by CED, and concentration-oriented evaluation of toxicity is more important than dose for CED.
14
Human situs inversus of the thoracoabdominal structures.
TL;DR: A region- or part-specific manner of the inverted morphology found in a male donated cadaver is demonstrated and the pathogenetic mechanisms of situs inversus in the human are discussed.
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