Yuhao Liu
Shihezi University
11 Papers
4 Citations
Yuhao Liu is an academic researcher from Shihezi University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 1, co-authored 1 publications.
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Papers
Integrated multi-omics profiling yields a clinically relevant molecular classification for esophageal squamous cell carcinoma.
Zhihua Liu,Yahui Zhao,Pengzhou Kong,Yuhao Liu,Jing Huang,Enwei Xu,Wenqing Wei,Guangyu Li,Xiaolong Cheng,Liyan Xue,Yi Li,Hongyan Chen,Shuqing Wei,Ruifang Sun,Heyang Cui,Yongsheng Meng,Meilin Liu,Yang Li,R. Feng,Xiao Yu,Rui Zhu,Yenan Wu,Lei Li,Bin Yang,Yanchun Ma,Jiawei Wang,Wenshuai Zhu,Dongmei Deng,Yanfeng Xi,Fang Wang,Hongyi Li,Shiping Guo,Xiaofei Zhuang,Xiaoyue Wang,Yuchen Jiao,Yongping Cui,Qimin Zhan +36 more
TL;DR: Wang et al. as discussed by the authors analyzed the whole genomic, epigenomic, transcriptomic, and proteomic data of 155 esophageal squamous cell carcinomas (ESCCs) and developed a classifier with 28 features to identify the IM subtype, which predicted anti-PD-1 therapy response with 85.7% sensitivity and 90% specificity.
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Mutant p53 activates hnRNPA2B1-AGAP1-mediated exosome formation to promote esophageal squamous cell carcinoma progression.
TL;DR: In this article , the authors performed whole-genome sequencing of 663 esophageal squamous cell carcinoma (ESCC) tumor tissues and paired normal tissues and found that the most frequent p53 mutations disrupt the inhibition of proliferation, migration, and invasion mediated by wild-type p53 in ESCC.
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Comprehensive characterization of posttranscriptional impairment-related 3′-UTR mutations in 2413 whole genomes of cancer patients
Wenqing Wei,Wenyan Gao,Qinglan Li,Yuhao Liu,Hongyan Chen,Yongping Cui,Zhong Sheng Sun,Zhihua Liu +7 more
TL;DR: Wang et al. as discussed by the authors explored the posttranscriptional function of 3' untranslated region (3'UTR) somatic mutations in tumorigenesis, and collected whole-genome data from 2413 patients across 18 cancer types.
Deubiquitinase USP8 increases ID1 stability and promotes esophageal squamous cell carcinoma tumorigenesis.
TL;DR: In this article , USP8 interacts with ID1, and increases the protein level and stability of ID1 by reducing its ubiquitination, and showed the importance of the USp8-ID1-TXNIP axis in promoting ESCC tumorigenesis.
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Comprehensive characterization of posttranscriptional impairment-related 3′-UTR mutations in 2413 whole genomes of cancer patients
Wenqing Wei,Wenyan Gao,Qinglan Li,Yuhao Liu,Hongyan Chen,Yongping Cui,Zhong Sheng Sun,Zhihua Liu +7 more
TL;DR: Wang et al. as discussed by the authors explored the posttranscriptional function of 3' untranslated region (3'UTR) somatic mutations in tumorigenesis, and collected whole-genome data from 2413 patients across 18 cancer types.