Yueming Long
Sun Yat-sen University
7 Papers
Yueming Long is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 4, co-authored 4 publications.
Chat about Author
Papers
Intradermal delivery of STAT3 siRNA to treat melanoma via dissolving microneedles.
Jingtong Pan,Wenyi Ruan,Mengyao Qin,Yueming Long,Tao Wan,Kaiyue Yu,Yuanhao Zhai,Chuanbin Wu,Yuehong Xu +8 more
TL;DR: In vivo experiments indicated that topical application of STAT3 siRNA PEI complex delivered by dissolving MNs into skin can effectively suppress the development of melanoma through silencing STAT3 gene, and the inhibition effect is dose-dependent.
Enzymatic Nitrogen Insertion into Unactivated C-H Bonds.
Soumitra V. Athavale,Shilong Gao,Anuvab Das,Sharath Chandra Mallojjala,Edwin Alexander Garzón Alfonzo,Yueming Long,Jennifer S. Hirschi,Frances H. Arnold +7 more
TL;DR: New-to-nature heme-containing nitrene transferases were used as starting points for the directed evolution of enzymes to selectively aminate and amidate unactivated C(sp3)-H sites, presenting a new biochemical logic for accessing nitrogen-containing compounds.
65
Dual roles of TPGS based microemulsion for tacrolimus: Enhancing the percutaneous delivery and anti-psoriatic efficacy.
Tao Wan,Jingtong Pan,Yueming Long,Kaiyue Yu,Yixuan Wang,Wenhui Pan,Wenyi Ruan,Mengyao Qin,Chuanbin Wu,Yuehong Xu +9 more
TL;DR: In this study, the dual roles of Tocopheryl Polyethylene Glycol 1000 Succinate (TPGS) based microemulsion for tacrolimus (TAC) to enhance TAC percutaneous delivery and anti-psoriatic efficacy are demonstrated.
48
Effects of nanoparticles with hydrotropic nicotinamide on tacrolimus: permeability through psoriatic skin and antipsoriatic and antiproliferative activities.
Tao Wan,Wenhui Pan,Yueming Long,Kaiyue Yu,Sibo Liu,Wenyi Ruan,Jingtong Pan,Mengyao Qin,Chuanbin Wu,Yuehong Xu +9 more
TL;DR: The histological study showed that the combination of NPs with NIC presented a synergistic effect on antipsoriasis after FK506 incorporation into NPs combined with NIC hydrotropic system, which might ultimately increase the therapeutic effect and minimize the systemic side effects by reducing the overall dose of Fk506.
Combination of hydrotropic nicotinamide with nanoparticles for enhancing tacrolimus percutaneous delivery.
Wenhui Pan,Mengyao Qin,Guoguang Zhang,Yueming Long,Wenyi Ruan,Jingtong Pan,Zushuai Wu,Tao Wan,Chuanbin Wu,Yuehong Xu +9 more
TL;DR: The results confirmed that NPs–NIC synergistically enhanced the permeation of the drug into the skin and it is a novel potential strategy based on a nano-sized carrier for FK506 to treat skin diseases.