Yucheng Chen
Brigham and Women's Hospital
5 Papers
5 Citations
Yucheng Chen is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Left ventricular hypertrophy & Hypertrophic cardiomyopathy. The author has an hindex of 3, co-authored 5 publications.
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Papers
T1 Measurements Identify Extracellular Volume Expansion in Hypertrophic Cardiomyopathy Sarcomere Mutation Carriers With and Without Left Ventricular Hypertrophy
Carolyn Y. Ho,Siddique Abbasi,Tomas G. Neilan,Ravi V. Shah,Yucheng Chen,Bobak Heydari,Allison L. Cirino,Neal K. Lakdawala,E. John Orav,Arantxa González,Begoña López,Javier Díez,Michael Jerosch-Herold,Raymond Y. Kwong +13 more
TL;DR: Myocardial ECV is increased in HCM sarcomere mutation carriers even in the absence of LVH, providing additional support that fibrotic remodeling is triggered early in disease pathogenesis.
Myocardial Extracellular Volume Fraction From T1 Measurements in Healthy Volunteers and Mice: Relationship to Aging and Cardiac Dimensions
Tomas G. Neilan,Otavio R. Coelho-Filho,Otavio R. Coelho-Filho,Ravi V. Shah,Ravi V. Shah,Siddique Abbasi,Bobak Heydari,Eri Watanabe,Yucheng Chen,Damien Mandry,Francois Pierre-Mongeon,Francois Pierre-Mongeon,Ron Blankstein,Raymond Y. Kwong,Michael Jerosch-Herold +14 more
TL;DR: In healthy volunteers, the myocardial ECV ranges from 0.23 to 0.33, has acceptable test characteristics, and is associated with age, left atrial volume, and left ventricular mass, while in mice, the ECV also increases with age and strongly correlates with the extent of myocardia fibrosis.
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CMR quantification of infarct tissue heterogeneity and remote myocardial fibrotic burden during convalescent phase following acute myocardial infarction (MI) provided strong and complementary evidence of ventricular arrhythmogenicity from quantitative microvolt T-wave alternans testing (the NHLBI PROSPECT-CMR study)
Bobby Heydari,Shuaib M Abdullah,Evan Appelbaum,Damien Mandry,Ron Blankstein,Yucheng Chen,Jiazuo H. Feng,Karl-Philipp Kienle,Elliott M. Antman,Heidi Lumish,Sanjeev A. Francis,Henry Gewirtz,Udo Hoffmann,Daniel E. Forman,Lahn Fendelander,Roger Plaisted,Rob J. van der Geest,Michael Jerosch-Herold,Raymond K. Kwong +18 more
TL;DR: It is postulate that these patterns of ischemic structural/arrhythmogenic affiliations during convalescent infarct healing, likely reflect differences in depolarization/repolarization characteristics of different post-ischemic myocardium and sympathetic innervation.
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T1 measurements identify extracellular volume expansion in a genotyped hypertrophic cardiomyopathy population with and without left ventricular hypertrophy
Siddique Abbasi,Ravi V. Shah,Ravi V. Shah,Tomas G. Neilan,Tomas G. Neilan,Bobby Heydari,Yucheng Chen,Michael Jerosch-Herold,Raymond Y. Kwong,Carolyn Y. Ho +9 more
TL;DR: Measuring T1 relaxation times with contrast cardiac magnetic resonance (CMR) allows robust quantification of the cardiac extracellular volume (ECV) and noninvasive assessment of diffuse myocardial fibrosis.
Quantitative T1 mapping and the fibrotic index in normal healthy volunteers; relationship to aging and cardiac dimensions
Tomas G. Neilan,Eri Watanabe,Otavio R. Coelho-Filho,Ravi V. Shah,Yucheng Chen,Bobby Heydari,Ron Blankstein,Raymond Y. Kwong,Michael Jerosch-Herold +8 more
TL;DR: In healthy volunteers, the fibrotic index has acceptable test characteristics, has a range from 0.23 to 0.33, and is associated with age, LA volume and LV mass.