Yuan Ping
National University of Singapore
15 Papers
39 Citations
Yuan Ping is an academic researcher from National University of Singapore. The author has contributed to research in topics: Gene delivery & Polyethylenimine. The author has an hindex of 13, co-authored 15 publications. Previous affiliations of Yuan Ping include Beijing University of Chemical Technology & Agency for Science, Technology and Research.
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Papers
Chitosan-functionalized graphene oxide as a nanocarrier for drug and gene delivery.
Hongqian Bao,Yongzheng Pan,Yuan Ping,Nanda Gopal Sahoo,Tongfei Wu,Lin Li,Jun Li,Leong Huat Gan +7 more
TL;DR: The covalent functionalization of graphene oxide (GO) with chitosan (CS) is successfully accomplished via a facile amidation process, and the resulting GO-CS/pDNA nanoparticles exhibit reasonable transfection efficiency in HeLa cells at certain nitrogen/phosphate ratios.
886
Star-Shaped Cationic Polymers by Atom Transfer Radical Polymerization from β-Cyclodextrin Cores for Nonviral Gene Delivery
TL;DR: A comparison of the transfection efficiencies between CDPD and P(DMAEMA) homopolymer indicates that the unique star-shaped architecture involving the CD core can enhance the gene transfections efficiency.
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Thermo- and pH-Responsive Association Behavior of Dual Hydrophilic Graft Chitosan Terpolymer Synthesized via ATRP and Click Chemistry
TL;DR: A comb-like dual hydrophilic graft chitosan terpolymer was synthesized by means of atom transfer radical polymerization (ATRP) and click chemistry as discussed by the authors.
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Comb-shaped copolymers composed of hydroxypropyl cellulose backbones and cationic poly((2-dimethyl amino)ethyl methacrylate) side chains for gene delivery.
TL;DR: The approach to well-defined comb-shaped cationic copolymers provides a versatile means for tailoring the functional structure of nonviral gene vectors to meet the requirements of strong DNA-condensing ability and high transfection capability.
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Functionalization of Chitosan via Atom Transfer Radical Polymerization for Gene Delivery
TL;DR: A series of new degradable cationic polymers composed of biocompatible chitosan backbones and poly((2‐dimethyl amino)ethyl methacrylate) (P(DMAEMA)) side chains of different length were designed as highly efficient gene vectors via ATRP, which exhibited good ability to condense plasmid DNA into nanoparticles with positive charge at nitrogen/phosphorus (N/P) ratios of 4 or higher.
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