19 Papers
62 Citations
Yuan Li is an academic researcher from Peking Union Medical College Hospital. The author has contributed to research in topics: Single-nucleotide polymorphism & Genome-wide association study. The author has an hindex of 7, co-authored 19 publications. Previous affiliations of Yuan Li include Peking Union Medical College & Qingdao University.
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Papers
Positive association of genetic variations in the phospholipase C-like 1 gene with dermatomyositis in Chinese Han.
Qian Wang,Si Chen,Yuan Li,Ping Li,Chanyuan Wu,Ziyan Wu,Qingjun Wu,Fei Sun,Jing Li,Wenjie Zheng,Chuiwen Deng,Fengchun Zhang,Yongzhe Li +12 more
TL;DR: A positive association between PLCL1 polymorphisms andDM patients and DM patients with ILD was observed, indicating that PLCL 1 might be the susceptibility gene for DM patients in Chinese Han.
21
Association of MCP-1-2518A/G polymorphism with susceptibility to autoimmune diseases: a meta-analysis
Si Chen,Chuiwen Deng,Chaojun Hu,Jing Li,Xiaoting Wen,Ziyan Wu,Yuan Li,Fengchun Zhang,Yongzhe Li +8 more
TL;DR: It was showed that the MCP-1-2518-A allele confers susceptibility to Asian patients with RA and European patients with CD, and for A allele vs. G allele, significant increased risk of autoimmune diseases could be found.
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Association of FCGR2A/FCGR3A variant rs2099684 with Takayasu arteritis in the Han Chinese population.
Si Chen,Xiaoting Wen,Jing Li,Yuan Li,Liubing Li,Xinping Tian,Hui Yuan,Fengchun Zhang,Yongzhe Li +8 more
TL;DR: The SNP rs2099684 in FCGR2A/FCGR3A can be considered a genetic risk factor for TA in the Chinese Han population, and further insights into the etiopathogenesis of TA are provided.
•Journal Article
A single-nucleotide polymorphism of CCL21 rs951005 T>C is associated with susceptibility of polymyositis and such patients with interstitial lung disease in a Chinese Han population.
Si Chen,Qian Wang,Chan Yuan Wu,Qing Jun Wu,Yuan Li,Zi Yan Wu,Ping Li,Fei Sun,Wen Jie Zheng,Chui Wen Deng,Fengchun Zhang,Yongzhe Li +11 more
TL;DR: This was the first study to demonstrate that the CCL21 gene SNP (rs951005) might confer genetic predisposition to PM patients or such patients with ILD in a Chinese Han population.
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Single nucleotide polymorphisms of IL12B are associated with Takayasu arteritis in Chinese Han population
Xiaoting Wen,Si Chen,Si Chen,Ping Li,Jing Li,Ziyan Wu,Yuan Li,Liubing Li,Hui Yuan,Xinping Tian,Fengchun Zhang,Yongzhe Li +11 more
TL;DR: SNPs in the IL12B and IL6 region may be considered a high-risk factor for TA in Chinese Han population and provide further clues for research into the pathogenesis of TA.
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