Background: In the United States, one in six children are affected by neurodevelopmental disorders, and polybrominated diphenyl ethers (PBDEs) in flame-retardant chemicals are measured ubiquitously...

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Developmental PBDE Exposure and IQ/ADHD in Childhood: A Systematic Review and Meta-analysis

Critical review of soil contamination by polybrominated diphenyl ethers (PBDEs) and novel brominated flame retardants (NBFRs); concentrations, sources and congener profiles.

Synthesis of a novel PEPA-substituted polyphosphoramide with high char residues and its performance as an intumescent flame retardant for epoxy resins

A review of human exposure to polybrominated diphenyl ethers (PBDEs) in China

The Yangtze River has been a source of life and prosperity for the Chinese people for centuries and is a habitat for a remarkable variety of aquatic species. But the river suffers from huge amounts of urban sewage, agricultural effluents, and industrial wastewater as well as ship navigation wastes along its course. With respect to the vast amounts of water and sediments discharged by the Yangtze River, it is reasonable to ask whether the pollution problem may be solved by simple dilution. This article reviews the past two decades of published research on organic pollutants in the Yangtze River and several adjacent water bodies connected to the main stream, according to a holistic approach. Organic pollutant levels and potential effects of water and sediments on wildlife and humans, measured in vitro, in vivo, and in situ, were critically reviewed. The contamination with organic pollutants, including polycyclic aromatic hydrocarbons, polychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs), polychlorinated dibenzo-p-dioxins/polychlorinated dibenzofurans, polybrominated diphenyl ethers (PBDEs), perfluorinated compounds (PFCs), and others, of water and sediment along the river was described. Especially Wuhan section and the Yangtze Estuary exhibited stronger pollution than other sections. Bioassays, displaying predominantly the endpoints mutagenicity and endocrine disruption, applied at sediments, drinking water, and surface water indicated a potential health risk in several areas. Aquatic organisms exhibited detectable concentrations of toxic compounds like PCBs, OCPs, PBDEs, and PFCs. Genotoxic effects could also be assessed in situ in fish. To summarize, it can be stated that dilution reduces the ecotoxicological risk in the Yangtze River, but does not eliminate it. Keeping in mind an approximately 14 times greater water discharge compared to the major European river Rhine, the absolute pollution mass transfer of the Yangtze River is of severe concern for the environmental quality of its estuary and the East China Sea. Based on the review, further research needs have been identified.

Solution by dilution?--A review on the pollution status of the Yangtze River.

Polybrominated diphenyl ethers fate in China: a review with an emphasis on environmental contamination levels, human exposure and regulation

Inappropriate production, storage and use of chemical could cause chemical incident. Chemical registration will contribute to the safe management of chemical. Represented by U.S. TSCA (Toxic Substances Control Act) regulations and the European REACH (Registration, Evaluation and Authorization of Chemicals), the awareness of building chemical registrations or chemical database is raising. By carrying out extensive research and comparing the chemical registration regulation status of eight selected countries/regions, the study is to compare the current management status of chemical registration in different developed and developing countries, which may provide information and overview for preventing, controlling and reducing chemical incident, improving safe management of chemical, and supporting the development of chemical registration database.

A Comparative Review on Chemical Registration Management Regulations

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Polybrominated diphenyl ethers fate in China: a review with an emphasis on environmental contamination levels, human exposure and regulation

A Comparative Review on Chemical Registration Management Regulations