Yuan Chen
5 Papers
Yuan Chen is an academic researcher. The author has contributed to research in topics: Medicine & Cancer research. The author has an hindex of 2, co-authored 4 publications.
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Papers
Reprogramming of palmitic acid induced by dephosphorylation of ACOX1 promotes β-catenin palmitoylation to drive colorectal cancer progression
Qian Zhang,Xiaoya Yang,Jinjie Wu,Shu-Biao Ye,Junli Gong,Wai Ming Cheng,Zhanhao Luo,Jing Yu,Yugeng Liu,Wanyi Zeng,Chen Liu,Zhi G. Xiong,Yuan Chen,Zhen He,P. Lan +14 more
TL;DR: Zhang et al. as discussed by the authors identified that metabolic enzyme acyl-CoA oxidase 1 (ACOX1) suppresses colorectal cancer (CRC) progression by regulating palmitic acid (PA) reprogramming.
Effects of Auricularia auricula Polysaccharides on Gut Microbiota and Metabolic Phenotype in Mice
Qian Liu,Xin An,Yuan Chen,Yuxuan Deng,Haili Niu,Ruiqiong Ma,Haoan Zhao,Wei Cao,Xiaoru Wang,Meng Wang +9 more
TL;DR: The relative abundance levels of Lactobacillus johnsonii, Weissella cibaria, Kosakonia cowanii, Enterococcus faecalis, Bifidobacterium animalis and Bacteroides uniformis were markedly up-regulated, while the relative abundance of Firmicutes bacterium M10-2 was down-regulated.
Therapeutic role of ursodeoxycholic acid in colitis-associated cancer via gut microbiota modulation
Qilang He,Jinjie Wu,Jia Ke,Qiang Zhang,Wanyi Zeng,Zhanhao Luo,Junli Gong,Yuan Chen,Zhen He,Ping Lan +9 more
TL;DR: It is suggested that UDCA intervention could reshape intestinal gut homeostasis, facilitating colonization of Akkermansia and preventing and treating colitis and CAC.
19
Enteral nutrition promotes the remission of colitis by gut bacteria-mediated histidine biosynthesis.
Wanyi Zeng,Jinjie Wu,Hongyu Xie,Haoyang Xu,Dayi Liang,Qilang He,Xiaoya Yang,Chen Liu,Junli Gong,Qiang Zhang,Zhanhao Luo,Yuan Chen,Zhenyv He,Ping Lan +13 more
TL;DR: This study suggests that EN-induced F. rodentium accumulation protects against colitis in mice via gut bacteria-mediated histidine biosynthesis via gut bacteria-mediated histidine biosynthesis.
4
Dynamic heterogeneity of colorectal cancer during progression revealed clinical risk-associated cell types and regulations in single-cell resolution and spatial context
Haoxian Ke,Zhihao Li,Peisi Li,Shu-Biao Ye,Tuo Hu,Chi Zhang,Ming Yuan,Yuan Chen,Xianrui Wu,Ping Lan +9 more
TL;DR: In this article , the dynamics of tumor heterogeneity during colorectal cancer (CRC) progression have not been elucidated and the authors used the Palantir algorithm and metabolic states were assessed by using scMetabolism.