Yu Wang
Northeast Normal University
7 Papers
46 Citations
Yu Wang is an academic researcher from Northeast Normal University. The author has contributed to research in topics: Toxicity & Absorption (skin). The author has an hindex of 6, co-authored 7 publications.
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Papers
Evaluation of toxicity data to green algae and relationship with hydrophobicity
TL;DR: Relationships between toxicity and hydrophobicity demonstrated that no difference was observed for non-polar narcotics within different exposure periods (24, 48, 72, and 96 h) or response variables (yield and growth rate) for polar narcotics.
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Relationship between lethal toxicity in oral administration and injection to mice: effect of exposure routes.
TL;DR: Regression analysis showed that log 1/LD₅₀ in oral route was related to the toxicity in injection route, which indicates that tissue distribution of compounds between blood and target site is a very rapid process, leading to log 1/(LD) in injection greater than those in oral administration.
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Discrimination of excess toxicity from narcotic effect: Influence of species sensitivity and bioconcentration on the classification of modes of action
TL;DR: The toxicity data of 2624 chemicals to fish, Daphniamagna, Tetrahymenapyriformis and Vibriofischeri were used to investigate the effects of species sensitivity and bioconcentration on excess toxicity, and the results showed that 47 chemical classes were identified as having the same modes of action (MOAs) to all four species, but more than half of the classes were identify as having different MOAs.
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The discrimination of excess toxicity from baseline effect: Effect of bioconcentration
TL;DR: The results showed that some compounds identified as reactive compounds exhibit excess toxicity, but some do not, and the foundation in the discrimination of excess toxicity from baseline effect is based on the linear relationship between log BCF and hydrophobicity expressed as log KOW, however, logBCF is not linearly related with log Kow for all the compounds.
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Investigation on baseline toxicity to rats based on aliphatic compounds and comparison with toxicity to fish: Effect of exposure routes on toxicity
TL;DR: The results showed that rat toxicity varies around a constant for classified compounds or homologues, and very close critical body residues (CBRs) calculated from percentage of absorption and bioconcentration factors indicate that most of aliphatic chemicals may share the same modes of toxic action between rat and fish species.
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