19 Papers
17 Citations
Yu Liu is an academic researcher from University of Tennessee Health Science Center. The author has contributed to research in topics: Prefrontal cortex & Spatial memory. The author has an hindex of 9, co-authored 19 publications. Previous affiliations of Yu Liu include University of Tennessee.
Chat about Author
Papers
Whisker barrel cortex delta oscillations and gamma power in the awake mouse are linked to respiration
Junji Ito,Snigdha Roy,Yu Liu,Ying Cao,Max L. Fletcher,Lu Lu,John D. Boughter,Sonja Grün,Detlef H. Heck +8 more
TL;DR: It is reported that delta band oscillation in spike and local field potential activity in the whisker barrel cortex of awake mice is phase locked to respiration, and LFP oscillations in the gamma frequency band are amplitude modulated in phase with the respiratory rhythm.
Breathing as a Fundamental Rhythm of Brain Function
Detlef H. Heck,Samuel S. McAfee,Yu Liu,Abbas Babajani-Feremi,Roozbeh Rezaie,Walter J. Freeman,James W. Wheless,Andrew C. Papanicolaou,Miklós Ruszinkó,Yury Sokolov,Robert Kozma +10 more
TL;DR: It is argued that respiration, via multiple sensory pathways, contributes a rhythmic component to the ongoing cortical activity and is suggested that this rhythmic activity modulates the temporal organization of cortical neurodynamics, thereby linking higher cortical functions to the process of breathing.
Hippocampal sharp-wave ripples in awake mice are entrained by respiration
TL;DR: It is shown that the timing of SWR events is modulated by the respiratory cycle, with a significantly increased probability of SWRs during the early expiration phase, which represents a possible neuronal mechanism for a direct influence of the respiratory Cycle on memory function.
Minimally invasive highly precise monitoring of respiratory rhythm in the mouse using an epithelial temperature probe.
TL;DR: A new method for recording the rhythm of respiration in awake mice with high precision, without damaging or irritating the nasal epithelium is described.
53
A CNS-permeable Hsp90 inhibitor rescues synaptic dysfunction and memory loss in APP-overexpressing Alzheimer's mouse model via an HSF1-mediated mechanism.
Bin Wang,Yu Liu,L. Huang,J. Chen,Jing Jing Li,Ruishan Wang,Eunhee Kim,Chen Yi,C. Justicia,Kazuko Sakata,Hao Chen,A. Planas,Rennolds S. Ostrom,Wu Bo Li,Guang Yang,Michael P. McDonald,R. Chen,Detlef H. Heck,Francesca-Fang Liao +18 more
TL;DR: It is demonstrated here that chronic treatment with a proprietary Hsp90 inhibitor compound (OS47720) not only elicits a heat-shock-like response but also offers synaptic protection in symptomatic Tg2576 mice, a model of Alzheimer’s disease, without noticeable systemic toxicity.