Yu Hao
13 Papers
2 Citations
Yu Hao is an academic researcher. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 2, co-authored 10 publications.
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Papers
MGF360-9L Is a Major Virulence Factor Associated with the African Swine Fever Virus by Antagonizing the JAK/STAT Signaling Pathway
Keshan Zhang,Bo Yang,Chaochao Shen,Ting Zhang,Yu Hao,Dajun Zhang,Huanan Liu,Xijuan Shi,Guoli Li,Jinke Yang,Dan Li,Zixiang Zhu,Hong Tian,Fan Yang,Yi Ru,Weijun Cao,Jianhong Guo,Jijun He,Haixue Zheng,Xiangtao Liu +19 more
TL;DR: The results showed that MGF360-9L may help ASFV escape the host immunity by degrading STAT1 and STAT2 and thus inhibiting IFN-β signaling and is also an important virulence factor of AsFV.
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ZBP1: A Powerful Innate Immune Sensor and Double-Edged Sword in Host Immunity
Yu Hao,Bo Yang,Jinke Yang,Xijuan Shi,Xing Yang,Dajun Zhang,D. Zhao,Wen‐Sheng Yan,Lingling Chen,Haixue Zheng,Keshan Zhang,Xiangtao Liu +11 more
TL;DR: The mechanisms of Z BP1 signaling, the effects of ZBP1 signaling on host immunity and pathogenic infection, and various antagonistic strategies of host and pathogen against ZBP 1 are reviewed.
Functional Analysis and Proteomics Profiling of Extracellular Vesicles From Swine Plasma Infected by African Swine Fever Virus
Guowei Xu,Xijuan Shi,Huanan Liu,Chaochao Shen,Bo Yang,Ting Zhang,Xuehui Chen,D. Zhao,Jinke Yang,Yu Hao,Huimei Cui,Xingguo Yuan,Xiangtao Liu,Keshan Zhang,Haixue Zheng +14 more
TL;DR: It is demonstrated that extracellular vesicles play a critical role in ASFV replication and transmission and cause significant differences in the protein profile encapsulated in extrace Cellular Vesicles.
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Identification and analysis of the interaction network of African swine fever virus D1133L with host proteins
Yu Hao,Jinke Yang,Bo Yang,Ting Zhang,Xijuan Shi,Xing Yang,Dajun Zhang,D. Zhao,Wen‐Sheng Yan,Lingling Chen,Xiangtao Liu,Haixue Zheng,Keshan Zhang +12 more
TL;DR: In this article , the authors used co-immunoprecipitation combined with liquid chromatography-mass spectrometry to investigate the protein-protein interaction network of ASFV D1133L protein in porcine kidney PK-15 cells.
African swine fever virus MGF360-9L promotes viral replication by degrading the host protein HAX1.
Jinke Yang,Bo Yang,Yu Hao,Xijuan Shi,Xing Yang,Dajun Zhang,D. Zhao,Wen‐Sheng Yan,Lingling Chen,Xintian Bie,Guohui Chen,Zixiang Zhu,Dan Li,Chaochao Shen,Guoli Li,Xiangtao Liu,Haixue Zheng,Keshan Zhang +17 more
TL;DR: The biological function of HAX1 in inhibiting ASFV replication was demonstrated and mechanism of MGF360–9L-linked K48 ubiquitin chain responsible for this inhibition was demonstrated.
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