Yu-Chen Chen
Academia Sinica
10 Papers
Yu-Chen Chen is an academic researcher from Academia Sinica. The author has contributed to research in topics: Biology & Gene. The author has an hindex of 1, co-authored 2 publications. Previous affiliations of Yu-Chen Chen include National Taiwan University.
Chat about Author
Papers
Genome-wide, integrative analysis of circular RNA dysregulation and the corresponding circular RNA-microRNA-mRNA regulatory axes in autism.
Yen-Ju Chen,Yen-Ju Chen,Chia-Ying Chen,Te-Lun Mai,Chih-Fan Chuang,Yu-Chen Chen,Sachin Kumar Gupta,Laising Yen,Yi-Da Wang,Trees-Juen Chuang,Trees-Juen Chuang +10 more
TL;DR: A role for circRNA dysregulation and the corresponding circRNA-microRNA-mRNA axes in ASD pathophysiology is supported by the first systems-level view of landscape of circRNA regulatory networks in ASD cortex samples.
FL-circAS: an integrative resource and analysis for full-length sequences and alternative splicing of circular RNAs with nanopore sequencing.
Tai-Wei Chiang,Song-En Jhong,Yu-Chen Chen,Chia-Ying Chen,Wei-Sheng Wu,Trees-Juen Chuang +5 more
TL;DR: FL-circAS provides user-friendly interfaces for browsing, searching, analyzing, and downloading data, serving as the first resource for discovering full-length circRNAs at the isoform level.
8
Whole-genome-sequence-based characterization of an NDM-5-producing uropathogenic Escherichia coli EC1390
Tran Thi Dieu Thuy,Hsu Feng Lu,Peiting Kuo,Wei Hung Lin,Tzu-Ping Lin,Yi-Tzu Lee,Tran Thi Thuy Duong,Ming Cheng Wang,Yi-Hong Lee,Li Li Wen,Yu-Chen Chen,Cheng-Yen Kao +11 more
TL;DR: In this article , an extensively-drug resistant (XDR) NDM-5-producing Escherichia coli EC1390 from a UTI patient was isolated and characterized by using whole-genome sequencing (WGS) in combination with phenotypic assays.
Whole-genome-sequence-based characterization of an NDM-5-producing uropathogenic Escherichia coli EC1390
Tran Thi Dieu Thuy,Hsu Feng Lu,Peiting Kuo,Wei Hung Lin,Tzu-Ping Lin,Yi Lee,Tran Thi Thuy Duong,Ming Cheng Wang,Yi-Hong Lee,Li Li Wen,Yu-Chen Chen,Cheng-Yen Kao +11 more
TL;DR: In this paper , an extensively-drug resistant (XDR) NDM-5-producing Escherichia coli EC1390 from a UTI patient was isolated and characterized by using whole-genome sequencing (WGS) in combination with phenotypic assays.
Detecting intragenic trans-splicing events from non-co-linearly spliced junctions by hybrid sequencing
Yu-Chen Chen,Chia-Ying Chen,Tai-Wei Chiang,Ming-Hsien Chan,Michael Hsiao,Huei-Mien Ke,Isheng J. Tsai,Trees-Juen Chuang +7 more
TL;DR: A bioinformatics pipeline (NCLscan-hybrid), which integrated short and long RNA-seq reads to minimize false positives and proposed out-of-circle and rolling-circle long reads to distinguish between intragenic ts-RNAs and circRNAs, and experimentally validated that one ts-RNA played an important role for p53-mediated apoptosis through affecting the PERK/eIF2a/ATF4/CHOP signaling pathway in breast cancer cells.
3