Young-Sun Lee
28 Papers
4 Citations
Young-Sun Lee is an academic researcher. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 3, co-authored 20 publications.
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Papers
Therapeutic mechanisms and beneficial effects of non-antidiabetic drugs in chronic liver diseases
Young Jun Chang,Pil Soo Sung,Eileen L. Yoon,Hye Won Lee,Jeong-Ju Yoo,Young-Sun Lee,Jihyun An,Do Seon Song,Young Youn Cho,Seung U. Kim,Yoon Jun Kim +10 more
TL;DR: Several non–antidiabetic drugs have shown beneficial effects in improving liver histology, aminotransferase level, and metabolic parameters and reducing risks of hepatocellular carcinoma and mortality, without significant safety concerns, in patients with CLD.
MRE-based NASH score for diagnosis of nonalcoholic steatohepatitis in patients with nonalcoholic fatty liver disease
Young-Sun Lee,Ji Eun Lee,Hyon-Seung Yi,Young Kul Jung,Dae Won Jun,Ji Hoon Kim,Yeon Seok Seo,Hyung J. Kim,Baek Hui Kim,Jeong Woo Kim,Chang-Hee Lee,Jong Eun Yeon,Juneyoung Lee,Soon Ho Um,Kwan Soo Byun +14 more
TL;DR: MRE-based NASH score is a useful and accurate non-invasive biomarker for diagnosis of NASH in patients with NAFLD and internal validation via bootstrapping indicated the satisfactory accuracy ofNASH diagnosis.
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Genotyping and Molecular Diagnosis of Hepatitis A Virus in Human Clinical Samples Using Multiplex PCR-Based Next-Generation Sequencing
Geum Young Lee,Won-Keun Kim,Seungchan Cho,Kyung-Min Park,Jongwoon Kim,Seungho Lee,Jingyeong Lee,Young-Sun Lee,Ji Hoon Kim,Kwan Soo Byun,Jin Won Song +10 more
TL;DR: The VP3 region in serum and stool samples showed sensitive detection of HAV with differences of quantification that did not exceed <10 copies/μL than the consensus VP4 region using quantitative PCR (qPCR), and might be a potential candidate for tracking the genotypic origin of emerging HAV outbreaks.
The spectrum of magnetic resonance imaging proton density fat fraction (MRI-PDFF), magnetic resonance spectroscopy (MRS), and two different histopathologic methods (artificial intelligence vs. pathologist) in quantifying hepatic steatosis
TL;DR: In this article , a spectrum of values of MRI-PDFF, FFMRS, and FFs measured by two different histopathologic methods (artificial intelligence (AI) and pathologist) were provided to evaluate the correlation among them, and the diagnostic performance of MRIPDFF and MRS for grading hepatic steatosis.
Improved anti-fibrotic effects by combined treatments of simvastatin and NS-398 in experimental liver fibrosis models
Seong Hee Kang,Hyung J. Kim,Ji Won Hwang,Mi-Jung Kim,Young-Sun Lee,Young Kul Jung,Baek-hui Kim,Hae Chul Park,Yeon Seok Seo,Ji Hoon Kim,Jong Eun Yeon,Soon Ho Um,Kwan Soo Byun +12 more
TL;DR: The combination of simvastatin and NS-398 resulted in a synergistic anti-fibrotic effect through multiple pathways, offering a theoretical insight into the possible clinical application of this strategy for the treatment of advanced liver diseases with hepatic fibrosis.