Young-Joon Park
Ajou University
61 Papers
106 Citations
Young-Joon Park is an academic researcher from Ajou University. The author has contributed to research in topics: Medicine & East Asia. The author has an hindex of 12, co-authored 50 publications.
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Papers
Comparison of a solid SMEDDS and solid dispersion for enhanced stability and bioavailability of clopidogrel napadisilate.
Dong Wuk Kim,Min Seok Kwon,Abid Mehmood Yousaf,Prabagar Balakrishnan,Jong Hyuck Park,Dong Shik Kim,Beom-Jin Lee,Young-Joon Park,Chul Soon Yong,Jong Oh Kim,Han-Gon Choi +10 more
TL;DR: SD showed significantly improved oral bioavailability compared to solid SMEDDS and CB powder, and was recommended as an alternative for the clopidogrel-based oral formulation.
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Dysregulation of NRF2 in Cancer: from Molecular Mechanisms to Therapeutic Opportunities.
TL;DR: The mechanisms whereby NRF2 is dysregulated in cancer and its contribution to the tumor development and radiochemoresistance are reviewed and new insights to develop selectiveNRF2 inhibitors are provided.
Highly efficient gene silencing and bioimaging based on fluorescent carbon dots in vitro and in vivo
Seongchan Kim,Yuri Choi,Ginam Park,Cheolhee Won,Young-Joon Park,Younghoon Lee,Byeong Su Kim,Dal-Hee Min +7 more
TL;DR: It is found that CD nanoparticles (NPs) enhance the cellular uptake of siRNA, via endocytosis in tumor cells, with low cytotoxicity and unexpected immune responses.
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Paclitaxel-loaded hyaluronan solid nanoemulsions for enhanced treatment efficacy in ovarian cancer.
Joo-Eun Kim,Young-Joon Park +1 more
TL;DR: PTX-HSN is a highly effective nanosystem with a high MTD for delivering PTX to ovarian cancers characterized by CD44 overexpression, enhanced active tumor targeting, and low toxicity.
Development of novel cilostazol–loaded solid SNEDDS using a SPG membrane emulsification technique: Physicochemical characterization and in vivo evaluation
Omer Mustapha,Kyung Soo Kim,Shumaila Shafique,Dong Shik Kim,Sung Giu Jin,Youn Gee Seo,Yu Seok Youn,Kyung Taek Oh,Beom-Jin Lee,Young-Joon Park,Chul Soon Yong,Jong Oh Kim,Han-Gon Choi +12 more
TL;DR: This novel solid SNEDDS developed using a membrane emulsification technique represents a potentially powerful oral delivery system for cilostazol and gave significantly higher initial plasma concentrations and AUC compared to the drug powder, suggesting its improved oral bioavailability.
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