14 Papers
You Wu is an academic researcher from Zhejiang Chinese Medical University. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 2, co-authored 2 publications.
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Papers
The role of ER stress and ATP/AMPK in oxidative stress meditated hepatotoxicity induced by citrinin.
Jing Wu,Chenglin Yang,Mengran Yang,Zengenni Liang,You Wu,Xiangyi Kong,Hui Fan,Siqi Wang,Can Ning,Wen-na Xiao,Ye Jin,Jine Yi,Zhihang Yuan +12 more
TL;DR: Zhang et al. as discussed by the authors studied the mechanism of citrinin-induced hepatotoxicity in L02 cells and showed that the liver injury can be aggravated by activating ROS-ER stress-AMPK signaling pathway.
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Activation of AQP4, p66Shc and endoplasmic reticulum stress is involved in inflammation by carrageenan and is suppressed by argirein, a derivative of rhein.
TL;DR: It is examined that aquaporin 4, p66Shc and activating transcription factor (ATF‐6) might be involved in carrageenan‐induced rat paw inflammation and be reversed by argirein, rhein and indometacin, but not l‐arginine.
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Betulinic acid mitigates zearalenone-induced liver injury by ERS/MAPK/Nrf2 signaling pathways in mice.
Jinghua Yu,Jiayan Li,You Wu,Mengran Yang,Yun-Hui Chen,Naidong Wang,Ji Wang,Zhihang Yuan,Jine Yi,Chenglin Yang +9 more
TL;DR: Zearalenone (ZEA) is a mycotoxin commonly found in cereals and feedstuffs, which can induce oxidative stress and inflammation to cause liver damage in humans and animals as mentioned in this paper .
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Citrinin-Induced Hepatotoxicity in Mice Is Regulated by the Ca2+/Endoplasmic Reticulum Stress Signaling Pathway
TL;DR: Results showed a possible underlying molecular mechanism for CTN that induced hepatocyte apoptosis in mice by the regulation of the Ca2+/ER stress signaling pathway.
Betulinic acid alleviates zearalenone-induced uterine injury in mice.
Chenglin Yang,Yun-Hui Chen,Mengran Yang,Jiayan Li,You Wu,Hui Fan,Xiangyi Kong,Can Ning,Siqi Wang,Wen-na Xiao,Zhihang Yuan,Jine Yi,Jing Wu +12 more
TL;DR: The uterus is an important target organ attacked by ZEA, and BA showed a good therapeutic effect, and the regulatory effect of ZEA on the uterus was reversed after BA treatment.
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