Prior uterine evacuation of pregnancy as independent risk factor for preterm birth: a systematic review and metaanalysis.

Recurrent spontaneous abortion (RSA) is usually defined as three or more spontaneous abortions prior to 20–28 weeks gestation. RSA affects approximately 2–5% of all women of childbearing age, and it brings tremendous psychological and psychiatric trauma to the women and also results in economic burden. The causes could be female age, anatomical and chromosomal abnormalities, genetic, endocrinological, placental anomalies, infection, smoking and alcohol consumption, psychological factor, exposure to environmental factors such as heavy metal, environment pollution, and radiation.

Definition and Multiple Factors of Recurrent Spontaneous Abortion.

Induced abortion (IA) has been associated with a lower risk of preeclampsia among nulliparous women, but it remains unclear whether this association differs by method (either surgical or medical) or timing of IA. We performed a nested case-control study of 12,650 preeclampsia cases and 50,600 matched control deliveries identified in the Medical Birth Register of Finland from 1996 to 2010. Data on number, method, and timing of IAs were obtained through a linkage with the Registry of Induced Abortions. Odds ratios and 95% confidence intervals were calculated. Overall, prior IA was associated with a lower risk of preeclampsia, with odds ratios of 0.9 (95% confidence interval (CI): 0.9, 1.0) for 1 prior IA and 0.7 (95% CI: 0.5, 1.0) for 3 or more IAs. Differences in the associations between IA and preeclampsia by timing and method of IA were small, with odds ratios of 0.8 (95% CI: 0.6, 1.1) for late (≥12 gestation weeks) surgical abortion and 0.9 (95% CI: 0.7, 1.2) for late medical abortion. There was no association between IA in combination with a history of spontaneous abortion and risk of preeclampsia. In conclusion, prior IA only was associated with a slight reduction in the risk of preeclampsia.

Induced Abortions and the Risk of Preeclampsia Among Nulliparous Women

This Evidence Overview provides a summary of the evidence on reducing the burden of unintended pregnancies in terms of two main packages of care: family planning and safe abortion. For each of these packages the scope and magnitude of benefits to women and to broader society is reviewed and the component interventions and delivery modalities outlined. The main body of the paper then synthesizes the evidence on interventions to reduce barriers to the supply of and demand for these services including estimates of cost-effectiveness. (excerpt)

Improving reproductive maternal and newborn health: reducing unintended pregnancies. Evidence overview. A working paper (version 1.0).

The effect of method and gestational age at termination of pregnancy on future obstetric and perinatal outcomes: a register-based cohort study in Aberdeen, Scotland

The influence of medical abortion compared with surgical abortion on subsequent pregnancy outcome

OBJECTIVE To analyze and evaluate the acceptability of mifepristone compatible with misoprostone versus conventional surgical abortion among women under unwanted early pregnancy, so as to help the unexpected pregnant women to choose the satisfactory abortion, and to provide the evidence for clinicians to make a proper clinical decision METHODS Six medical databases were searched, including MEDLINE, EMBASE, Cochrane library, CBMdisc, CNKI and VIP, together with twelve journals hand-searched, and references of included studies additionally searched Two qualified reviewers reviewed the original articles, evaluating qualities of articles, and extracting data independently After heterogeneity test, the data was pooled using Revman software if capable, or descriptive analysis was applied RESULTS In total, nine original clinical controlled trials were included, containing 3565 cases Before abortion, more unwanted pregnant women chose the medical abortion because they believed medical abortion was less painful than surgical abortion (OR = 46651, 95% CI: 9137 - 238188), but medical abortion was less time-consuming than surgical abortion (OR = 002, 95% CI: 001 - 006) After abortion, satisfaction with medical abortion was similar to that with surgical abortion, with insignificant difference (P = 089) However, second choice and recommendation rates of medical abortion were much higher than those of surgical abortion with OR and 95% CI as 272, 213 - 347 and 419, 216 - 1116, respectively CONCLUSIONS Medical abortion was less painful than surgical abortion and the rate of second choice and recommendation to others were all also higher than those of surgical abortion However, the process of medical abortion was not as quick as surgical abortion but the satifacation of both methods seemed similar Therefore, the two artificial abortion methods were not recommended to replace each other at the present time

Study on Meta analysis regarding the acceptability of medical abortion compared with surgical abortion

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The influence of medical abortion compared with surgical abortion on subsequent pregnancy outcome

Study on Meta analysis regarding the acceptability of medical abortion compared with surgical abortion