18 Papers
88 Citations
You Li is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Bipolar disorder & Single-nucleotide polymorphism. The author has an hindex of 13, co-authored 17 publications. Previous affiliations of You Li include Chinese Academy of Sciences.
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Papers
Gold nanoparticles for high-throughput genotyping of long-range haplotypes
Peng Chen,Dun Pan,Chunhai Fan,Chunhai Fan,Jianhua Chen,Ke Huang,Dongfang Wang,Honglu Zhang,You Li,Guoyin Feng,Pei-Ji Liang,Lin He,Lin He,Lin He,Yongyong Shi +14 more
TL;DR: It is shown that through a combination of capillary sequencing and polymerase chain reaction assisted by gold nanoparticles, it is possible to identify several DNA variations that are associated with age-related macular degeneration and psoriasis on significant regions of human genomic DNA.
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A Genome-wide association study reveals association between common variants in an intergenic region of 4q25 and high-grade myopia in the Chinese Han population
Zhiqiang Li,J. Qu,Xun Xu,Xiangtian Zhou,Haidong Zou,Ning Wang,Tao Li,Xiaohan Hu,Qian Zhao,Peng Chen,Wenjin Li,Ke Huang,Jun Yang,Zangdong He,Jue Ji,Ti Wang,Junyan Li,You Li,Jie Liu,Zhen Zeng,Guoyin Feng,Lin He,Lin He,Lin He,Yongyong Shi +24 more
TL;DR: A locus in an intergenic region at 4q25, within MYP11 (4q22-q27, OMIM: 609994), was found to be associated with high-grade myopia, and provides a more accurate locus for HM.
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Common SNPs and haplotypes in DGKH are associated with bipolar disorder and schizophrenia in the Chinese Han population
Zhen Zeng,Zhen Zeng,Ting Wang,Ting Wang,Tao Li,Tao Li,You Li,You Li,Peng Chen,Peng Chen,Qingzhu Zhao,Qingzhu Zhao,Jianjun Liu,Jianjun Liu,Jia Li,Jia Li,G. Y. Feng,Li-xian He,Li-xian He,Li-xian He,Yongyong Shi,Yongyong Shi +21 more
TL;DR: Common SNPs and haplotypes in DGKH are associated with bipolar disorder and schizophrenia in the Chinese Han population and could be a cause for concern in the future.
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FoxP2 is significantly associated with schizophrenia and major depression in the Chinese Han population.
Tao Li,Zhen Zeng,Qian Zhao,Ti Wang,Ke Huang,Junyan Li,You Li,Jie Liu,Zhiyun Wei,Yang Wang,Guoyin Feng,Lin He,Yongyong Shi +12 more
TL;DR: This study indicated that the rare variant rs10447760 in FoxP2 may play an important role in schizophrenia and major depression in the Chinese Han population.
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Positive association between GRIN2B gene and bipolar disorder in the Chinese Han Population
Qian Zhao,Ronglin Che,Zhao Zhang,Peng Wang,Jun Li,You Li,Ke Huang,Wei Tang,Guoyin Feng,Klaus Lindpaintner,Lin He,Lin He,Lin He,Yongyong Shi,Yongyong Shi +14 more
TL;DR: Three single-nucleotide polymorphisms (SNPs) of the GRIN2B gene in a set of 480 unrelated bipolar disorder patients and 480 unrelated genetically matched normal controls were significantly associated, suggesting GRin2B as having a role in the etiology of bipolar disorder.
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