Yoshikazu Higami
Tokyo University of Science
162 Papers
1.1K Citations
Yoshikazu Higami is an academic researcher from Tokyo University of Science. The author has contributed to research in topics: White adipose tissue & Adipose tissue. The author has an hindex of 33, co-authored 157 publications. Previous affiliations of Yoshikazu Higami include University of Wisconsin-Madison & Nagasaki University.
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Papers
The poly(adenosine diphosphate-ribose) polymerase inhibitor PJ34 reduces pulmonary ischemia-reperfusion injury in rats.
Go Hatachi,Tomoshi Tsuchiya,Takuro Miyazaki,Keitaro Matsumoto,Naoya Yamasaki,Naoyuki Okita,Atsushi Nanashima,Yoshikazu Higami,Takeshi Nagayasu +8 more
TL;DR: The PARP-i decreased inflammation and tissue damage caused by pulmonary I/R injury and may be correlated with its antioxidative efficacy.
22
Acute stress response in calorie-restricted rats to lipopolysaccharide- induced inflammation
Tomoshi Tsuchiya,Yoshikazu Higami,Toshimitsu Komatsu,Kenji Tanaka,Sumihisa Honda,Haruyoshi Yamaza,Takuya Chiba,Hiroyoshi Ayabe,Isao Shimokawa +8 more
TL;DR: The present results suggest that CR attenuates liver injury without suppression of the proinflammatory response, and that the protective effect emerges from constitutively, rather than inductively, expressed gene products.
20
Pleomorphic Adenoma of the Breast: Report of a Case
Nobuo Mochinaga,Takashi Yatsugi,Shigeo Tomokawa,Tamotsu Ishida,Hiroshi Ohtani,Yoshikazu Higami +5 more
TL;DR: The patient presented with a hard mass, 3 cm in diameter, located just beneath the left areola, and physical examination suggested a diagnosis of breast carcinoma; however, the findings of both ultrasonography and mammography indicated a benign neoplasm.
20
Effect of Leptin on Hypothalamic Gene Expression in Calorie-Restricted Rats
Toshimitsu Komatsu,Takuya Chiba,Haruyoshi Yamaza,Kazuo To,Hiroaki Toyama,Yoshikazu Higami,Isao Shimokawa +6 more
TL;DR: Results indicated that leptin administration reversed the upregulated expression of neuropeptide Y and agouti-related protein genes in CR rats, suggesting the possibility of a role for the leptin-ARH pathway in the effect of CR.
20
Japanese Herbal Medicine Ninjinyoeito Mediates Its Orexigenic Properties Partially by Activating Orexin 1 Receptors.
Kanako Miyano,Kaori Ohshima,Nozomi Suzuki,Saho Furuya,Yuki Yoshida,Miki Nonaka,Yoshikazu Higami,Kazumi Yoshizawa,Hideaki Fujii,Yasuhito Uezono +9 more
TL;DR: The finding suggest that NYT and citrus unshiu peel could increase food intake via activation of orexigenic OX1R-expressing neurons in the hypothalamus through activation of hyperphagia signaling in the central nervous system.