Yongping Yue
University of Iowa
7 Papers
9 Citations
Yongping Yue is an academic researcher from University of Iowa. The author has contributed to research in topics: Adeno-associated virus & Transduction (genetics). The author has an hindex of 7, co-authored 7 publications.
Chat about Author
Papers
Circular Intermediates of Recombinant Adeno-Associated Virus Have Defined Structural Characteristics Responsible for Long-Term Episomal Persistence in Muscle Tissue
Dongsheng Duan,Prerna Sharma,Jusan Yang,Yongping Yue,Lorita Dudus,Yulong Zhang,Krishna J. Fisher,John F. Engelhardt +7 more
TL;DR: These studies suggest that certain structural characteristics of AAV circular intermediates may explain long-term episomal persistence with this vector and aid in the development of nonviral gene delivery systems with increased efficiency.
536
Expanding AAV packaging capacity with trans-splicing or overlapping vectors: a quantitative comparison.
TL;DR: Using the beta-galactosidase gene as template, trans-splicing approaches were threefold and 12-fold more effective in generating full-length transgene products than the overlapping vector approach.
271
A new dual-vector approach to enhance recombinant adeno-associated virus-mediated gene expression through intermolecular cis activation.
TL;DR: A new dual-vector approach to enhance recombinant adeno-associated virus-mediated gene expression through intermolecular cis activation is presented.
211
Structural analysis of adeno-associated virus transduction circular intermediates.
TL;DR: In this paper, a model for the formation of AAV circular intermediates by recombination/ligation between ITR ends of panhandle single-stranded AAV genomes was proposed.
108
Formation of Adeno-Associated Virus Circular Genomes Is Differentially Regulated by Adenovirus E4 ORF6 and E2a Gene Expression
Dongsheng Duan,Prerna Sharma,Lorita Dudus,Yulong Zhang,Salih Sanlioglu,Ziying Yan,Yongping Yue,Yihong Ye,Rachael Lester,Jusan Yang,Krishna J. Fisher,John F. Engelhardt +11 more
TL;DR: The formation of AAV circular intermediates appears to represent a new pathway for AAV genome conversion, which is consistent with the head-to-tail concatemerization associated with latent-phase persistence of rAAV.
101