We set out to retrospectively review the clinical and imaging features of patients with post-radiation sarcoma, especially in the head and neck region. We reviewed the records of 4194 patients with carcinoma of the head and neck region who had a history of radiation. They had undergone CT and/or MRI. Medical records were reviewed for the primary diagnosis, radiation history and latency period to the development of sarcoma. The patients included four men and two women with a mean age of 64.5 years. The mean latency period for the development of sarcoma was 11.5 years. Primary diagnoses were maxillary carcinoma, nasopharyngeal carcinoma, adenoid cystic carcinoma of the oral floor, tonsilar carcinoma, soft palate carcinoma and tongue carcinoma. Histopathological examinations revealed osteosarcoma, spindle cell sarcoma, chondrosarcoma, malignant peripheral nerve sheath tumour, spindle cell carcinoma and malignant fibrous histiocytoma, respectively. Common findings were a heterogeneous and well-enhanced soft tissue mass and bone destruction. There is at present little or no prospect for the effective prevention of radiation-induced sarcoma of the head and neck. This emphasizes the importance of the earliest possible diagnosis for such patients. The imaging findings are not diagnosis specific, but strict follow-up within the radiation field by CT and MRI and an appreciation of the expected latency period may help to provide the diagnosis. When radiotherapy is performed for head and neck neoplasms, periodic follow-up observations may be necessary for many years.

Imaging findings of radiation-induced sarcoma of the head and neck.

ObjectiveTo study the surg ical treatment of tonsillar cancer. Methods Twenty-four patients with tonsillar cancer were treated with surgery and postoperative radiotherapy. The choice of surgical procedure was decided on the condition of the lesion. The tumor was resected through the transoral approach, mandibular swing approach, mandiblar resection approach or hyoid approach. Surg ical defect was repaired by pectoralis major myocutaneous flap, sternohyoid myo fascial flap, tongue flap or soft palate flap. Results The 3- and 5-year surv ival rates were 76.0% and 60.8%. Function of chewing, deglutition, respiration and speech was restored well. Conclusion Method of total resection of the to nsillar carcinoma through the optimum approach is best chosen according to the c ondition of the lesion, while preserving the oropharyngeal function. When combin ed with postoperative radiotherapy, the survival rate and quality of life of pat ients can be improved.

Surgical treatment of tonsillar cancer

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Surgical treatment of tonsillar cancer