Yoko Horikawa
Osaka University
11 Papers
133 Citations
Yoko Horikawa is an academic researcher from Osaka University. The author has contributed to research in topics: Thrombopoietin & Thrombopoiesis. The author has an hindex of 8, co-authored 11 publications.
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Papers
Growth response of acute myeloblastic leukemia cells to recombinant human thrombopoietin
Itaru Matsumura,Yuzuru Kanakura,Takashi Kato,Hirokazu Ikeda,Jun Ishikawa,Yoko Horikawa,Koji Hashimoto,Yasuhiro Moriyama,Tohru Tsujimura,Tetsuo Nishiura +9 more
TL;DR: Results suggested that c-mpl may be functional in terms of supporting proliferation of various types of AML cells and that TPO may contribute, at least in part, to abnormal growth of the cells, especially in combination with other hematopoietic growth factors.
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The Biologic Properties of Recombinant Human Thrombopoietin in the Proliferation and Megakaryocytic Differentiation of Acute Myeloblastic Leukemia Cells
Itaru Matsumura,Yuzuru Kanakura,Takashi Kato,Hirokazu Ikeda,Yoko Horikawa,Jun Ishikawa,Hitoshi Kitayama,Tetsuo Nishiura,Yoshiaki Tomiyama,Hiroshi Miyazaki,Yuji Matsuzawa +10 more
TL;DR: RhTPO could not only support the proliferation of AML cells irrespective of AMl subtypes, but could also induce megakaryocytic differentiation, possibly through activation of GATA-1, Gata-2, and NF-E2.
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Decreased nitric oxide-mediated natural killer cell activation in chronic fatigue syndrome.
Megumu Ogawa,Tetsuo Nishiura,Masafumi Yoshimura,Yoko Horikawa,Hitoshi Yoshida,Yu Okajima,Itaru Matsumura,Jun Ishikawa,Hirohisa Nakao,Yoshiaki Tomiyama,Yoshio Kanayama,Yuzuru Kanakura,Yuji Matsuzawa +12 more
TL;DR: L‐Arginine, one of the essential amino acids, has been reported to have an immunomodulatory effect and the effect of L‐Arg on NK cells in chronic fatigue syndrome (CFS) patients has not been estimated.
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•Journal Article
Coexpression of thrombopoietin and c-mpl genes in human acute myeloblastic leukemia cells.
Itaru Matsumura,Yuzuru Kanakura,Hirokazu Ikeda,Jun Ishikawa,Hitoshi Yoshida,Yoko Horikawa,Tetsuo Nishiura,T. Tahara,Takashi Kato,H. Miyazaki,Yuji Matsuzawa +10 more
TL;DR: The results suggest that TPO may not commonly participate in the abnormal growth of AML cells as an extracellular autocrine growth factor.
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Functional role of cation-independent mannose 6-phosphate/insulin-like growth factor II receptor in cell adhesion and proliferation of a human myeloma cell line OPM-2
Tetsuo Nishiura,Takahiro Karasuno,Hitoshi Yoshida,Hirohisa Nakao,Megumu Ogawa,Yoko Horikawa,Masafumi Yoshimura,Yu Okajima,Yuzuru Kanakura,Yoshio Kanayama,Yuji Matsuzawa +10 more
TL;DR: Results suggest that CIM6P/IGF-II receptor may be functional in terms of supporting cell adhesion and proliferation of myeloma cells.
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