Yohan Kim
Mayo Clinic
21 Papers
55 Citations
Yohan Kim is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Medicine & Metastasis. The author has an hindex of 9, co-authored 21 publications. Previous affiliations of Yohan Kim include Lawson Health Research Institute & University of Western Ontario.
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Papers
Quantification of cancer cell extravasation in vivo
Yohan Kim,Yohan Kim,Karla C. Williams,Karla C. Williams,Carson T Gavin,Carson T Gavin,Emily Jardine,Emily Jardine,Ann F. Chambers,Ann F. Chambers,Hon S. Leong,Hon S. Leong +11 more
TL;DR: A rapid, reproducible and economical technique to evaluate cancer cell invasiveness by quantifying in vivo rates of cancer cell extravasation in the chorioallantoic membrane (CAM) of chicken embryos that can be used to identify and validate drugs with potential antimetastatic effects that specifically target cancer cellExtravasation.
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Leukemic extracellular vesicles induce chimeric antigen receptor T cell dysfunction in chronic lymphocytic leukemia.
Michelle J. Cox,Michelle J. Cox,Fabrice Lucien,Reona Sakemura,Justin C. Boysen,Yohan Kim,Paulina Horvei,Claudia Manriquez Roman,Michael J. Hansen,Erin E. Tapper,Elizabeth L. Siegler,Cynthia L. Forsman,Sydney B. Crotts,Kendall J. Schick,Mehrdad Hefazi,Michael W. Ruff,Ismail Can,Mohamad M. Adada,Evandro D. Bezerra,Lionel A. Kankeu Fonkoua,Wendy K. Nevala,Esteban Braggio,Wei Ding,Sameer A. Parikh,Neil E. Kay,Saad S. Kenderian +25 more
TL;DR: In this article, the authors used chronic lymphocytic leukemia (CLL) as a model to investigate the interactions between the tumor microenvironment and CART cells and found that CLL-derived EVs were able to induce a state of CART cell dysfunction characterized by phenotypical, functional and transcriptional changes of exhaustion.
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Magnetic resonance imaging for detecting and treatment monitoring of orthotopic murine bladder tumor implants.
TL;DR: The orthotopic tumor and MRI model described is ideal for preclinical evaluation of new potential intravesical chemotherapy and immunotherapy agents as well as detection and treatment monitoring of early stage Orthotopic murine bladder (MBT-2) tumor implants.
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Rab17 mediates differential antigen sorting following efferocytosis and phagocytosis.
TL;DR: Results indicate that macrophages prevent presentation of apoptotic cell-derived antigens by preferentially trafficking efferocytosed, but not phagocytose, materials away from the MHC class II loading compartment via the recycling endosome pathway.
FUS-CHOP promotes invasion in myxoid liposarcoma through a SRC/FAK/RHO/ROCK-dependent pathway
Juan Tornin,Francisco Hermida-Prado,Ranjit S. Padda,Ranjit S. Padda,M. Victoria Gonzalez,Carlos Alvarez-Fernandez,Veronica Rey,Lucia Martinez-Cruzado,Oscar Estupiñan,Sofía T. Menéndez,Lucia Fernandez-Nevado,Aurora Astudillo,Juan P. Rodrigo,Fabrice Lucien,Yohan Kim,Yohan Kim,Yohan Kim,Hon S. Leong,Hon S. Leong,Hon S. Leong,Juana M. García-Pedrero,Rene Rodriguez +21 more
TL;DR: Data uncover the involvement of SRC/FAK/RHO/ROCK signaling axis in FUS-CHOP–mediated invasion, thus providing a rationale for testing inhibitors of this pathway as potential novel antimetastatic agents for MRCLS treatment.
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