Yiying Wang
University of Arkansas for Medical Sciences
9 Papers
28 Citations
Yiying Wang is an academic researcher from University of Arkansas for Medical Sciences. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 5, co-authored 5 publications.
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Papers
Suppression of autophagy in osteocytes mimics skeletal aging.
Melda Onal,Marilina Piemontese,Jinhu Xiong,Yiying Wang,Li Han,Shiqiao Ye,Masaaki Komatsu,Martin K. Selig,Robert S. Weinstein,Haibo Zhao,Robert L. Jilka,Maria Almeida,Stavros C. Manolagas,Charles A. O'Brien +13 more
TL;DR: The results demonstrate that suppression of autophagy in osteocytes mimics, in many aspects, the impact of aging on the skeleton and suggest that a decline in Autophagy with age may contribute to the low bone mass associated with aging.
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Enforcing temporal control of maternal mRNA translation during oocyte cell‐cycle progression
TL;DR: Using antisense oligonucleotides to attenuate endogenous Musashi synthesis, it is shown that Musashi is critical for the initiation of early class mRNA translation and for the subsequent activation of CPE‐dependant mRNA translation.
Suppression of autophagy in osteocytes does not modify the adverse effects of glucocorticoids on cortical bone.
Marilina Piemontese,Melda Onal,Jinhu Xiong,Yiying Wang,Maria Almeida,Jeff D. Thostenson,Robert S. Weinstein,Stavros C. Manolagas,Charles A. O'Brien +8 more
TL;DR: Comparing the impact of prednisolone administration on the skeletons of adult mice in which autophagy was suppressed in osteocytes, via deletion of Atg7 with a Dmp1-Cre transgene, to their control littermates demonstrates that although glucocorticoids stimulate autophagic flux in osteocyte-enriched bone, suppression ofAutophagy in this cell type does not worsen the negative impact of glucoc Corticoids on the skeleton.
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Ringo/Cyclin-dependent Kinase and Mitogen-activated Protein Kinase Signaling Pathways Regulate the Activity of the Cell Fate Determinant Musashi to Promote Cell Cycle Re-entry in Xenopus Oocytes
Karthik Arumugam,Melanie C. MacNicol,Yiying Wang,Chad E. Cragle,Alan J. Tackett,Linda L. Hardy,Angus M. MacNicol +6 more
TL;DR: Musashi-directed mRNA translation induces MAP kinase signaling and establishes a positive feedback loop to amplify Musashi activity, suggesting an evolutionarily conserved mechanism to control Musashi-dependent target mRNA translation.
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Solasodine suppresses the metastasis of gastric cancer through claudin-2 via the AMPK/STAT3/NF-κB pathway.
TL;DR: In this paper , the role and mechanism of solasodine in inhibiting Gastric cancer (GC) metastasis was investigated, and it was shown that solasoda not only promoted cell death but also inhibited the migration and invasion of HGC27 and AGS cells.
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