Yixuan He
7 Papers
Yixuan He is an academic researcher. The author has contributed to research in topics: Medicine & Mesenchymal stem cell. The author has an hindex of 2, co-authored 2 publications.
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Papers
microRNA-27b shuttled by mesenchymal stem cell-derived exosomes prevents sepsis by targeting JMJD3 and downregulating NF-κB signaling pathway
TL;DR: In this article, the potential role and downstream molecular mechanism of exosomal microRNAs (miRs) derived from mesenchymal stem cells (MSCs) have been investigated.
Tumour‐associated macrophages in gastric cancer: From function and mechanism to application
TL;DR: Although the role of TAMs in GC remains controversial in clinical settings, clarifying their significance in the treatment selection and prognostic prediction of GC could support optimising TAM‐centred clinicaltherapy.
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Krüppel-Like Factor 6 Silencing Prevents Oxidative Stress and Neurological Dysfunction Following Intracerebral Hemorrhage via Sirtuin 5/Nrf2/HO-1 Axis.
TL;DR: KLF6 silencing alleviated neurological dysfunction and oxidative stress in ICH rats and diminished oxidative stress and neuronal apoptosis in OxyHb-induced neurons, whereas SIRT5 overexpression negated its effect.
Exosomes derived from NGF-overexpressing bone marrow mesenchymal stem cell sheet promote spinal cord injury repair in a mouse model
Siqiaozhi Li,Xin Liao,Yixuan He,H. S. Chen,Wei Zheng,Manshu Tang,Xiaohua Guo,Junhui Chen,Sean Hu,Jia Sun +9 more
TL;DR: In this paper , the function of bone marrow mesenchymal stem cells (BMSC) sheet in the progression of spinal cord injury and its underlying mechanism was elucidated, where NGF was highly expressed in the BMSC sheet-loaded Exos and facilitated neuronal differentiation of NSCs and axonal regeneration.
14
Comprehensive analysis of cuproptosis-related immune biomarker signature to enhance prognostic accuracy in gastric cancer
TL;DR: In this paper , the potential functional roles of cuproptosis-related immune genes (CRIGs) in GC and their values as biomarkers were analyzed using CRIG expression in GC scRNA-seq.