Yipeng Du
Peking University
21 Papers
103 Citations
Yipeng Du is an academic researcher from Peking University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 14, co-authored 17 publications. Previous affiliations of Yipeng Du include Chinese Academy of Sciences.
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Papers
Epigenetic regulation of autophagy by the methyltransferase EZH2 through an MTOR-dependent pathway
Fu Zheng Wei,Ziyang Cao,Xi Wang,Hui Wang,Mu Yan Cai,Tingting Li,Naoko Hattori,Donglai Wang,Yipeng Du,Boyan Song,Lin Lin Cao,Changchun Shen,Lina Wang,Haiying Wang,Yang Yang,Dan Xie,Fan Wang,Toshikazu Ushijima,Ying Zhao,Wei-Guo Zhu,Wei-Guo Zhu,Wei-Guo Zhu +21 more
TL;DR: It is reported that the methyltransferase EZH2 epigenetically represses several negative regulators of the MTOR (mechanistic target of rapamycin [serine/threonine kinase]) pathway, such as TSC2, RHOA, DEPTOR, FKBP11, RGS16 and GPI.
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ASEB: a web server for KAT-specific acetylation site prediction
TL;DR: This article provides KAT-specific acetylation site prediction as a web service and provides the online tool and R package for the method in the previous study, but several useful services are also included, such as the integration of protein–protein interaction information to enhance prediction accuracy.
SET7/9 regulates cancer cell proliferation by influencing β-catenin stability
Changchun Shen,Donglai Wang,Xiangyu Liu,Bo Gu,Yipeng Du,Fu-Zheng Wei,Lin-Lin Cao,Boyan Song,Xiaopeng Lu,Qiaoyan Yang,Qian Zhu,Tianyun Hou,Meiting Li,Lina Wang,Haiying Wang,Ying Zhao,Yang Yang,Wei-Guo Zhu,Wei-Guo Zhu +18 more
TL;DR: A novel mechanism by which Wnt/ β‐catenin signaling is regulated in response to oxidative stress is provided by su(var)3‐9, enhancer‐of‐zeste, trithorax (SET) domain‐containing protein 7 (SET7/9), a lysine methyltransferase, interacted with and methylated β‐ catenin, as demonstrated both in vitro and in vivo.
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ATM-mediated KDM2A phosphorylation is required for the DNA damage repair
Lin-Lin Cao,Fu-Zheng Wei,Yipeng Du,Boyan Song,Dong-Xin Wang,Changchun Shen,Xiaopeng Lu,Zhengyi Cao,Qiaoyan Yang,Yue Gao,Lina Wang,Ying Zhao,Hongbing Wang,Yinmo Yang,Wei-Guo Zhu,Wei-Guo Zhu +15 more
TL;DR: It is reported that ataxia-telangiectasia mutated ATM regulates the DNA damage response by phosphorylating lysine-specific demethylase 2A (KDM2A), a histone dem methylase that acts at sites of H3K36 dimethylation.
SIRT5 deacylates metabolism-related proteins and attenuates hepatic steatosis in ob/ob mice.
Yipeng Du,Hao Hu,Saisi Qu,Jifeng Wang,Chaoju Hua,Jialing Zhang,Peng Wei,Xiaolong He,Junfeng Hao,Pingsheng Liu,Fuquan Yang,Tingting Li,Taotao Wei +12 more
TL;DR: Hematic overexpression of SIRT5 ameliorated the metabolic abnormalities of ob/ob mice, probably through demalonylating and desuccinylating proteins in the main metabolic pathways.
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