Yingyu Chen
Huazhong Agricultural University
96 Papers
164 Citations
Yingyu Chen is an academic researcher from Huazhong Agricultural University. The author has contributed to research in topics: Mycobacterium tuberculosis & Mycobacterium bovis. The author has an hindex of 17, co-authored 96 publications.
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Papers
Indirubin Inhibits LPS-Induced Inflammation via TLR4 Abrogation Mediated by the NF-kB and MAPK Signaling Pathways.
Jin-lun Lai,Yu-hui Liu,Chang Liu,Mingpu Qi,Rui-ning Liu,Xifang Zhu,Qiu-ge Zhou,Yingyu Chen,Aizhen Guo,Changmin Hu +9 more
TL;DR: Indirubin effectively suppressed LPS-induced inflammation via TLR4 abrogation mediated by the NF-kB and MAPK signaling pathways and may be useful for mastitis prophylaxis.
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Mycoplasma bovis MBOV_RS02825 Encodes a Secretory Nuclease Associated with Cytotoxicity
TL;DR: It is a first report that MbovNase is an active nuclease, both secretory and membrane protein with ability to degrade NETs and induce apoptosis.
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Ivermectin Inhibits Bovine Herpesvirus 1 DNA Polymerase Nuclear Import and Interferes with Viral Replication.
Sohail Raza,Sohail Raza,Farzana Shahin,Wenjun Zhai,Hanxiong Li,Gualtiero Alvisi,Kui Yang,Xi Chen,Yingyu Chen,Chen Jianguo,Changmin Hu,Huanchun Chen,Aizhen Guo +12 more
- 13 Mar 2020
TL;DR: Treatment of cells with Ivermectin, an anti-parasitic drug which has been recently identified as an inhibitor of importin α/β-dependent nuclear transport, reduced UL42 nuclear import and specifically reduced BoHV-1 replication in a dose-dependent manner, while virus attachment and entry into cells were not affected.
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Evaluation of a Novel Chimeric B Cell Epitope-Based Vaccine against Mastitis Induced by Either Streptococcus agalactiae or Staphylococcus aureus in Mice
Haiyang Xu,Changmin Hu,Rui Gong,Yingyu Chen,Ningning Ren,Ganwen Xiao,Qian Xie,Minmin Zhang,Qin Liu,Aizhen Guo,Huanchun Chen +10 more
TL;DR: Histopathological examination of the mammary glands showed that rSip-ClfA immunization provided better protection of mammary gland tissue integrity against both S. agalactiae and S. aureus challenges.
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Identification of potential urine proteins and microRNA biomarkers for the diagnosis of pulmonary tuberculosis patients
Jieru Wang,Xiaojie Zhu,Xuekai Xiong,Pan Ge,Han Liu,Ningning Ren,Farhan Anwar Khan,Xia Zhou,Li Zhang,Xu Yuan,Xi Chen,Yingyu Chen,Changmin Hu,Ian D. Robertson,Huanchun Chen,Aizhen Guo +15 more
TL;DR: These novel urine biomarkers may significantly improve tuberculosis diagnosis and be increased to a greater extent in samples of smear-positive than smear-negative patients.
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