Yingqing Wang
Fujian Medical University
21 Papers
77 Citations
Yingqing Wang is an academic researcher from Fujian Medical University. The author has contributed to research in topics: Medicine & Parkinson's disease. The author has an hindex of 5, co-authored 7 publications.
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Papers
Gastrointestinal nervous system α-synuclein as a potential biomarker of Parkinson disease.
TL;DR: Gastrointestinal mucous biopsy could be regarded as a potential opportunity for the early-stage diagnostic exploration of PD, through the detection of &agr;-synuclein inclusions.
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Overexpression of PGC-1α Influences Mitochondrial Signal Transduction of Dopaminergic Neurons
Qinyong Ye,Wanling Huang,Dongzhu Li,Erwang Si,Juhua Wang,Yingqing Wang,Chun Chen,Xiaochun Chen +7 more
TL;DR: The overexpression of P GC-1α can inhibit MPP+-induced mitochondrial damage in SH-SY5Y cells, and PGC-1 α may realize the neuroprotective effects via the ERRα, PPARγ, and NRF-1 pathway.
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Association of pro-inflammatory diet with increased risk of all-cause dementia and Alzheimer's dementia: a prospective study of 166,377 UK Biobank participants
Yisen Shi,Fabin Lin,Yue-Ping Li,Yingqing Wang,Xiaochun Chen,Fangang Meng,Qinyong Ye,Guoen Cai +7 more
TL;DR: It is suggested that the association with DII and vascular and frontotemporal dementia was not significant, and the total volume of white matter hyperintensities increased with an increase in DII, whereas the volume of gray matter in the hippocampus decreased.
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Mitochondrial Effects of PGC-1alpha Silencing in MPP+ Treated Human SH-SY5Y Neuroblastoma Cells.
Qinyong Ye,Chun Chen,Erwang Si,Yousheng Cai,Juhua Wang,Wanling Huang,Dongzhu Li,Yingqing Wang,Xiaochun Chen +8 more
TL;DR: The finding indicates that small interfering RNA (siRNA) interference targeting the PGC-1 α gene could inhibit the function of mitochondria in several capacities and that the P GC-1α gene may modulate mitochondrial function by regulating the expression of ERRα, NRF-1, NRf-2 and PPARγ.
Beneficial effects of PGC-1α in the substantia nigra of a mouse model of MPTP-induced dopaminergic neurotoxicity.
Yingqing Wang,Chun Chen,Wanling Huang,Maoxin Huang,Juhua Wang,Xiaochun Chen,Qinyong Ye +6 more
- 21 Oct 2019
TL;DR: PGC-1α rescues the effects of MPTP-induced mitochondrial dysfunction in C57BL mice and finds significant improvement in motor behavior and increases in tyrosine hydroxylase expression in the substantia nigra (SN) in the brains of mice in the LVPGC+M group.
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