Yingchao Chen

TL;DR: Six amphiphilic Janus dendrimer primary structures self-assemble into uniform onion-like vesicles, which provide mimics of double-bilayer and multibilayer biological membranes with dimensions and number of bilayers predicted by the Janus compound concentration in water.

TL;DR: Solid injectable hydrogels, which are commonly referred to as 'shear-thinning and rehealing' materials, hold exciting promise for biomedical applications that require well-defined morphological and mechanical properties after delivery to a desired site through a shearing process.

TL;DR: An accelerated modular synthesis of six libraries containing 29 amphiphilic Janus dendrimers, employed to discover and predict functions via primary structures, is reported, suggesting the synthesis of Library 6 containing two simpler constitutional isomeric benzyl ester based amphiphiles that self-assemble in water into soft d endrimersomes and multidendrimerome dend rimersomes with predictable dimensions.

TL;DR: The applicability of Janus-GDs to dissect structure-activity relationships between programmable cell surface models and human lectins in a highly sensitive and physiologically relevant manner is illustrated.