6 Papers
1 Citations
Ying Luo is an academic researcher from Kunming University of Science and Technology. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 1, co-authored 1 publications.
Chat about Author
Papers
Senescent Fibroblasts Generate a CAF Phenotype through the Stat3 Pathway
TL;DR: Wang et al. as mentioned in this paper showed that senescent fibroblasts displayed CAF properties, including the highly expressed CAF markers, α-SMA and Vimentin, and CAF-specific factors, CXCL12, FGF10, IL6 and COL1A1, which significantly increased collagen contractile activity and promoted the migration and invasion of lung cancer cells, H1299 and A549.
p53N236S Activates Autophagy in Response to Hypoxic Stress Induced by DFO
Kang Gao,Huanhuan Zong,Kailong Hou,Yanduo Zhang,Ruyi Zhang,Dan Zhao,Xin Guo,Ying Luo,Shuting Jia +8 more
TL;DR: It is found that p53N236S mutant mouse embryonic fibroblasts resistant to deferoxamine (DFO) mimic a hypoxic environment and activates autophagy instead of inducing an apoptotic process in response to hypoxia stress to protect cells from death.
Inflammatory level under different p53 mutation status and the regulation role of curcumin in tumor microenvironment.
TL;DR: In this article , the authors compared the inflammatory level and macrophage profiles in tumor cells and tumor samples with different p53 mutations and found that a lower inflammatory level was maintained in immune organs and tumor cells with p53 point mutations than those with a null mutation.
3
Gain-of-Function p53N236S Mutation Drives the Bypassing of HRasV12-Induced Cellular Senescence via PGC–1α
TL;DR: In this article , the authors found that p53S increased the level and nuclear translocation of PGC-1α in late-stage p53s/++Ras cells (LS cells), which bypassed the OIS.
NCAPH plays important roles in human colon cancer
Liang Yin,Liping Jiang,Qiu-Shuo Shen,Qiu-Shuo Shen,Qiuxia Xiong,Xiao Zhuo,Long-Long Zhang,Hai-Jing Yu,Xiang Guo,Ying Luo,Jian Dong,Qing-Peng Kong,Cui-Ping Yang,Yongbin Chen +13 more
TL;DR: Findings reveal an important role of NCAPH in CC, indicating that NCAPH could be used as a new therapeutic target in future and Interestingly, the NCAPH high expression in tumor tissues of colon patients had a significantly better prognosis and survival rate than low-expression patients.