Ying Luan
4 Papers
Ying Luan is an academic researcher. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 1, co-authored 4 publications.
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Papers
Large-scale observational prospective cohort study of a multi-cancer early detection (MCED) test in symptomatic patients referred for cancer investigation.
Brian Nicholson,Dean A. Harris,Catherine A O'Doherty,P S Virdee,Sharon Tonner,M. Vargova,Lazarina Engonidou,Kaveh Riahi,Ying Luan,Sara Hiom,Harpal S. Kumar,Kathryn N. Kurtzman,Ly Me Yu,Sarah Pearson,Rafael Perera,Mark R. Middleton +15 more
TL;DR: In this paper , the authors evaluated the performance of a next-generation sequencing MCED test (GRAIL, LLC) using cell-free DNA (cfDNA) isolated from whole blood in symptomatic patients referred to cancer diagnostic clinics by their primary care physician.
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Abstract 6752: Patient (pt) characteristics, diagnostic journey, and cancer enrichment among pts with nonspecific signs and/or symptoms (s/sx) in the US community oncology setting: a real-world retrospective study
TL;DR: Benton et al. as mentioned in this paper examined pt characteristics, diagnostic journey, and cancer incidence of pts with nonspecific signs and/or symptoms within The US Oncology Network (index date) during the identification period from 1/1/2016 to 12/31/2020.
Multi-cancer early detection test in symptomatic patients referred for cancer investigation in England and Wales (SYMPLIFY): a large-scale, observational cohort study.
Brian Nicholson,Jason Oke,P S Virdee,Dean A. Harris,Catherine A O'Doherty,Zaed Z R Hamady,Vinay Sehgal,Andrew Millar,Louise C. Medley,Sharon Tonner,Lazarina Engonidou,Kaveh Riahi,Ying Luan,Sara Hiom,Harpal S. Kumar,Kathryn N. Kurtzman,Ly-Mee Yu,Sarah Pearson,FD Richard Hobbs,Rafael Perera,Mark R. Middleton +20 more
TL;DR: This first large-scale prospective evaluation of a methylation-based multicancer early detection (MCED) diagnostic test in a symptomatic population demonstrates the feasibility of using an MCED test to assist clinicians with decisions regarding urgency and route of referral from primary care.
Performance of a Cell-Free DNA-Based Multi-cancer Detection Test in Individuals Presenting With Symptoms Suspicious for Cancers.
Alan H. Bryce,David D. Thiel,Michael V. Seiden,Donald A. Richards,Ying Luan,Marie V. Coignet,Quan Zhang,N. Zhang,Earl Hubbell,Kathryn N. Kurtzman,Eric A. Klein +10 more
TL;DR: In this article , a multi-cancer detection test using a targeted methylation assay and machine learning classifiers was validated and optimized for screening in prospective, case-controlled Circulating Cell-free Genome Atlas (ClinicalTrials.gov identifier: NCT02889978) substudy 3.