Ying Liu
5 Papers
Ying Liu is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 1, co-authored 4 publications.
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Papers
Rolling back human pluripotent stem cells to an eight-cell embryo-like stage
Md Abdul Mazid,Carl Ward,Zhiwei Luo,Chuanyu Liu,Yunpan Li,Yiwei Lai,Liang Wu,Jinxiu Li,Wenqi Jia,Yu Jiang,Hao Liu,Lixin Fu,Yueli Yang,David P. Ibañez,Junjian Lai,Xiaoyu Wei,Juan An,Pengcheng Guo,Yue Yuan,Qiuting Deng,Yang Wang,Ying Liu,Fei Gao,Junwen Wang,Shahriar Zaman,Baoming Qin,Guangming Wu,Patrick H. Maxwell,Xun Xu,Longqi Liu,Wenjuan Li,Miguel A. Esteban +31 more
TL;DR: A transgene-free, rapid, and controllable method for producing 8C-like cells (8CLC) from human pluripotent stem cells (PSC) and single-cell analysis identified key molecular events and gene networks associated with this conversion.
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Single-cell RNA reveals a tumorigenic microenvironment in the interface zone of human breast tumors
Wei Yang,Meiyu Xu,Shuoqi Xu,Qingxian Guan,Shuaiming Geng,Juanhong Wang,Wei Wei,Hongwei Xu,Ying Liu,Yong Meng,Ming Qing Gao +10 more
TL;DR: A unique tumorigenic microenvironment of the interface zone of breast cancer is identified and allowed for deeper insights into the tumor microenvironment of breast cancer that will serve as a helpful resource for advancing breast cancer diagnosis and therapy.
6
Regulon active landscape reveals cell development and functional state changes of human primary osteoblasts in vivo
Shengran Wang,Yun Gong,Zun Wang,Xiang-he Meng,Zhe Luo,Christopher J. Papasian,Jonathan Greenbaum,Yisu Li,Qilan Liang,YiPing Chen,Xiaohuan Li,Qiu Xiang,Hiuxi Zhang,Ying Liu,Liang Cheng,Yihe Hu,Li-Jun Tan,Hui Shen,Hong-Mei Xiao,Hongwen Deng +19 more
TL;DR: In this article , the authors identify modules (regulons) of co-regulated genes by applying singlecell regulatory network inference and clustering to the single-cell RNA sequencing profiles of human osteoblasts and performed cell-specific network (CSN) analysis, reconstructed regulon activity-based osteoblast development trajectories, and validated the functions of important regulons both in vivo and in vitro.
N-myc downstream regulated gene 1 suppresses osteoblast differentiation through inactivating Wnt/β-catenin signaling
Xinjue Shi,Yunzhu Cen,Liying Shan,Lijie Tian,Endong Zhu,Hairui Yuan,Xiaoxia Li,Ying Liu,Baoli Wang +8 more
TL;DR: In this paper , the role of N-myc downstream regulated gene 1 (NDRG1) in the proliferation and differentiation of marrow stromal progenitor cells and the mechanism underlying the function was investigated.