Ying Han
Peking Union Medical College
15 Papers
36 Citations
Ying Han is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Zebrafish & Biology. The author has an hindex of 7, co-authored 11 publications.
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Papers
In silico ADME and Toxicity Prediction of Ceftazidime and Its Impurities
TL;DR: It is concluded that the beta-lactam ring of nucleus, the quaternary amine group at the C-3 side chain, and the acetates at theC-7 side chain of CAZ are the main toxic functional groups.
Cardiotoxicity evaluation of anthracyclines in zebrafish (Danio rerio).
TL;DR: Zebrafish may have a potential value for assessment of drug‐induced developmental cardiotoxicity, indicating that ANTs induced cardiot toxicity in zebrafish has similar effects in mammalian models.
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Embryo and Developmental Toxicity of Cefazolin Sodium Impurities in Zebrafish.
TL;DR: The results suggested that the structure of MMTD (2-mercapto-5-methyl-1, 3, 4-thiadiazole) is the main toxic functional group for embryo deformities; the 7-ACA (7-aminocephalosporanic acid) structure mainly affects motor nerve function; and both the M MTD and7-ACA structures are responsible for cardiac effects.
In vivo and in silico evaluations of survival and cardiac developmental toxicity of quinolone antibiotics in zebrafish embryos (Danio rerio).
TL;DR: In this paper, the relationship between different quinolone structures and toxicity in zebrafish embryos using in-vivo and in-silico methods was investigated using quantitative structure-toxicity relationship (QSTR) modeling.
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Microarray Expression Profiling and Raman Spectroscopy Reveal Anti-Fatty Liver Action of Berberine in a Diet-Induced Larval Zebrafish Model
TL;DR: A larval zebrafish model is employed to mimic the therapeutic effects of BBR in the pediatric population and the mechanisms underlying its hepatoprotection to provide molecular information for BBR on the prevention and treatment of pediatric NAFLD.