Ying Cheng
Zhejiang Chinese Medical University
6 Papers
Ying Cheng is an academic researcher from Zhejiang Chinese Medical University. The author has contributed to research in topics: Chemistry & Nanocarriers. The author has an hindex of 3, co-authored 5 publications.
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Papers
Targeted Manganese doped silica nano GSH-cleaner for treatment of Liver Cancer by destroying the intracellular redox homeostasis.
Hongxia Tang,Chaoqun Li,Yue Zhang,Hongyue Zheng,Ying Cheng,Jingjing Zhu,Xiaojie Chen,Zhihong Zhu,Ji-Gang Piao,Fanzhu Li +9 more
TL;DR: Target sorafenib loaded manganese doped silica nanoparticle (FaPEG-MnMSN@SFB) was constructed, which could destroy the intracellular redox homeostasis by consuming GSH and cause multi-path programmed cell death and could be a promising strategy for cancer therapy.
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iRGD and TGN co-modified PAMAM for multi-targeted delivery of ATO to gliomas.
Xiaowei Shi,Rui Ma,Yanping Lu,Ying Cheng,Xudong Fan,Jiafeng Zou,Hongyue Zheng,Fanzhu Li,Ji-Gang Piao +8 more
TL;DR: iRGD/TGN-based dual targeting by combining nanocarriers and targeting technology increased the amount of drug that crossed BBB, thus achieving targeted enrichment and activation of the drug in tumor tissue, and shows great promise for targeted glioma therapy.
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Microwave-triggered/HSP-targeted Gold Nano-system for Triple-negative Breast Cancer Photothermal Therapy
TL;DR: In vitro and in vivo results indicated that the induction through microwave irradiation could effectively activate the HSP70 overexpression in TNBC, thereby significantly improving the targeting ability, tumor accumulation and anti-tumor efficacy of cmHSP-AuNC.
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Novel Strategy of Gene Delivery System Based on Dendrimer Loaded Recombinant Hirudine Plasmid for Thrombus Targeting Therapy.
Chen Junjie,Yanping Lu,Ying Cheng,Rui Ma,Jiafeng Zou,Hongyue Zheng,Ruwei Wang,Zhihong Zhu,Fanzhu Li +8 more
TL;DR: Overall, this study takes the advantage of the unique advantages of hirudine, combining the genetic engineering, nanocarriers, and targeting technology, to achieve the targeted enrichment and activation the hirUDine fusion protein in the thrombus site, to improve the concentration of drugs in theThrom bus site, finally increasing the curative effect and reduce the risk of bleeding.
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A pH-responsive chiral mesoporous silica nanoparticles for delivery of doxorubicin in tumor-targeted therapy.
Kaijun Gou,Wei Xin,Jinyi Lv,Zihao Ma,Juqin Yang,Lin Zhao,Ying Cheng,Xuchun Chen,Rui Zeng,Heran Li +9 more
TL;DR: Wang et al. as mentioned in this paper developed a nano-drug delivery system with intelligent stimuli-responsive drug delivery in tumor microenvironment (TME). Based on chiral mesoporous silica nanoparticles (CMSN) with a chiral recognition function, a pH-responsive CMSN (CS-CMSN), was successfully prepared by chemical modification of chitosan (CS), and the related physicochemical properties, drug release performance, potential anti-tumor effect, and biological safety were studied.
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