Ying Chen
Zhejiang University
14 Papers
15 Citations
Ying Chen is an academic researcher from Zhejiang University. The author has contributed to research in topics: Conidiation & Fungal protein. The author has an hindex of 11, co-authored 13 publications.
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Papers
MDM2 promotes epithelial-mesenchymal transition and metastasis of ovarian cancer SKOV3 cells
Ying Chen,Dandan Wang,Yeping Wu,Dan Su,Tianyi Zhou,Renhua Gai,Yingying Fu,Lin Zheng,Qiaojun He,Hong Zhu,Bo Yang +10 more
TL;DR: It is demonstrated that MDM2 functions as a key factor to drive EMT and motility of ovarian SKOV3 cells, by facilitating the activation of TGF-β-Smad pathway, which results in the increased transcription of snail/slug and the subsequent loss of E-cadherin levels.
Polysarcosine brush stabilized gold nanorods for in vivo near-infrared photothermal tumor therapy
Hong Zhu,Ying Chen,Fangjie Yan,Jin Chen,Xinfeng Tao,Jun Ling,Bo Yang,Qiaojun He,Zheng-Wei Mao,Zheng-Wei Mao +9 more
TL;DR: The polysarcosine coated AuNRs had very low cytotoxicity and showed high efficacy for the ablation of cancer cells in vitro and did not cause obvious toxicity in vivo, suggesting promising potential in cancer therapy.
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Three mitogen-activated protein kinases required for cell wall integrity contribute greatly to biocontrol potential of a fungal entomopathogen.
TL;DR: Taken together, the CWI-required Bck1, Mkk1 and Slt2 are all positive, but differential, regulators of multi-stress tolerance and virulence perhaps due to interplay with the HOG pathway essential for osmoregulation, thereby contributing greatly to the biocontrol potential of the fungal entomopathogen.
Inactivation of hypoxia-induced YAP by statins overcomes hypoxic resistance tosorafenib in hepatocellular carcinoma cells
Tianyi Zhou,Lin-han Zhuang,Yan Hu,Yu-lu Zhou,Wen-kai Lin,Dandan Wang,Zi-qian Wan,Lin-Lin Chang,Ying Chen,Meidan Ying,Zi-bo Chen,Song Ye,Jianshu Lou,Qiaojun He,Hong Zhu,Bo Yang +15 more
TL;DR: It is found that hypoxia induced the nuclear translocation of Yes associate-Protein (YAP) and the subsequent transactivation of target genes that promote cell survival and escape apoptosis, thereby leading to sorafenib resistance, and statins, the inhibitors of hydroxymethylglutaryl-CoA reductase, could ameliorateHypoxia-induced nuclear translocated YAP and suppress mRNA levels of YAP target genes both in vivo and in vitro
Subcellular localization of five singular WSC domain‐containing proteins and their roles in Beauveria bassiana responses to stress cues and metal ions
TL;DR: A significance of each WSC protein for the B. bassiana adaptation to diverse habitats of host insects is indicated, as all the eGFP-tagged fusion proteins of Wsc1A-1E were evidently localized to the cell wall and membrane of transgenic hyphae.
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