Yin Wang
Peking Union Medical College
4 Papers
Yin Wang is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Heart failure & Medicine. The author has an hindex of 4, co-authored 4 publications.
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Papers
Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function
Li Wang,Peng Yu,Bingying Zhou,Jiangping Song,Zheng Li,Mingzhi Zhang,Guangran Guo,Yin Wang,Xiao Chen,Leng Han,Shengshou Hu +10 more
TL;DR: Transcriptome profiling of 21,422 single cells—including cardiomyocytes and neighbouring cells from healthy adults and patients with heart failure and in recovery, and delineate their cellular compositions and interaction networks provides insights into cell-type-targeted intervention of heart diseases.
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Single-Cell Reconstruction of Progression Trajectory Reveals Intervention Principles in Pathological Cardiac Hypertrophy
TL;DR: Cell crosstalk analysis revealed stagewise utilization of specific noncardiomyocytes during the deterioration of heart function and shed light on strategies for cell type- and stage-specific intervention in cardiac diseases.
188
Single-cell analysis of murine fibroblasts identifies neonatal to adult switching that regulates cardiomyocyte maturation.
Yin Wang,Fang Yao,Lipeng Wang,Zheng Li,Zongna Ren,Dandan Li,Mingzhi Zhang,Leng Han,Shi-Qiang Wang,Bingying Zhou,Li Wang +10 more
TL;DR: It is reported that switching of fibroblast subtypes from a neonatal to adult state and this drives cardiomyocyte maturation, and single-cell analysis is used to examine how the population of murine cardiac fibroblasts changes during development and affects maturation of cardiomeocytes.
Histone Variant H2A.Z is Required for the Maintenance of Smooth Muscle Cell Identity as Revealed by Single-Cell Transcriptomics.
Fang Yao,Peng Yu,Yue Li,Xinli Yuan,Zheng Li,Tao Zhang,Fei Liu,Yingbao Wang,Yingbao Wang,Yin Wang,Dandan Li,Baihui Ma,Chang Shu,Wei Kong,Bingying Zhou,Li Wang +15 more
TL;DR: In this article, Histone variants endow chromatin with specific structures, and play essential roles in development and diseases, but little is known about their roles in controlling cell identity and cell proliferation.