Yihao Tian
Wuhan University
24 Papers
135 Citations
Yihao Tian is an academic researcher from Wuhan University. The author has contributed to research in topics: Breast cancer & Cell growth. The author has an hindex of 12, co-authored 22 publications.
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Papers
CircRNA inhibits DNA damage repair by interacting with host gene
Xiaolong Xu,Jingwei Zhang,Yihao Tian,Yang Gao,Xin Dong,Wenbo Chen,Xiaoning Yuan,Weinan Yin,Jinjing Xu,Ke Chen,Chunjiang He,Chunjiang He,Lei Wei +12 more
TL;DR: It is demonstrated that circSMARCA5 can bind to its parent gene locus, forming an R-loop, which results in transcriptional pausing at exon 15 of SMarCA5, which revealed a new regulatory mechanism for circRNA on its host gene and provided evidence that circ SMAR CA5 may serve as a therapeutic target for drug-resistant breast cancer patients.
MicroRNA-610 inhibits the migration and invasion of gastric cancer cells by suppressing the expression of vasodilator-stimulated phosphoprotein.
TL;DR: It is demonstrated that VASP was upregulated by epidermal growth factor (EGF) and promoted the migration and invasion of gastric cancer cells and the identification of miR-610 as a novel miRNA regulated by EGF that targets VasP in gastriccancer cells suggests that EGF-miR610-VASP axis may be exploited for therapeutic intervention to inhibit gastric cancers progression and metastasis.
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Nuclear import of human sexual regulator DMRT1 is mediated by importin-β
TL;DR: Results suggest that zinc finger domain of D MRT1 functions as a nuclear localization signal and DMRT1 is transported into the nucleus in an importinbeta1-mediated manner.
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Nicotine prevents the apoptosis induced by menadione in human lung cancer cells.
TL;DR: It is suggested that nicotine has potential effect in lung cancer genesis, especially in patients with undetectable early tumor development and development of specific NF-kappaB inhibitors would represent a potentially exciting new pharmacotherapy for tobacco-related lung cancer.
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Silencing lncRNA SNHG6 suppresses proliferation and invasion of breast cancer cells through miR-26a/VASP axis.
Kai Li,Yanbin Ma,Yihao Tian,Xiaolong Xu,Yang Gao,Yanqi He,Wenting Pan,Jingwei Zhang,Chunjiang He,Lei Wei +9 more
TL;DR: The important role of the SNHG6/miR-26a/VASP regulatory network in the development of breast cancer is revealed, and a reference for exploring new pathogenesis and biomarkers of Breast cancer is provided.
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