Yichen Zhao
4 Papers
Yichen Zhao is an academic researcher. The author has contributed to research in topics: Aptamer & Chemistry. The author has an hindex of 2, co-authored 3 publications.
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Papers
Label-free and Dye-free Fluorescent Sensing of Tetracyclines Using a Capture-Selected DNA Aptamer.
TL;DR: In this article , the authors used DNA aptamers to detect tetracyclines and achieved a dissociation constant of 147 nM measured by isothermal titration calorimetry.
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Metal and pH-Dependent Aptamer Binding of Tetracyclines Enabling Highly Sensitive Fluorescence Sensing
TL;DR: In this article , the effect of pH and metal ions on the sensor was studied, and it was shown that Mg2+ ions are required for the binding of OTC5 to its target with an optimal concentration of 2 mM.
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An aptamer array for discriminating tetracycline antibiotics based on binding-enhanced intrinsic fluorescence.
TL;DR: In this article , the authors analyzed the top 100 sequences from the previous selection library and found that OTC43 aptamer was more selective for oxytetracycline with a limit of detection (LOD) of 0.7 nM OTC, OTC22 was more select for DOX (LOD 0.4 nM), and OTC2 was more selectively for TC (0.3 nM).
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Characterization of the Binding Properties of Ten Aptamers Using the Intrinsic Fluorescence of Oxytetracycline.
TL;DR: This is the first study of ten different aptamers for the same target, providing fundamental insights into aptamer binding and bioanalytical applications and showing a correlation between fluorescence lifetime and degree of fluorescence enhancement.
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