10 Papers
4 Citations
Yichen Cai is an academic researcher from Tianjin University of Traditional Chinese Medicine. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 2, co-authored 2 publications.
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Papers
Neuroinflammation in Ischemic Stroke: Focus on MicroRNA-mediated Polarization of Microglia.
TL;DR: In this article, the authors reviewed the dynamic response of microglia after a stroke and assessed how specific miRNAs affect the behavior of reactive micro-glia and concluded that miRNas may be useful novel therapeutic targets to improve stroke outcomes and modulate neuroinflammation.
Edaravone Dexborneol Treatment Attenuates Neuronal Apoptosis and Improves Neurological Function by Suppressing 4-HNE-Associated Oxidative Stress After Subarachnoid Hemorrhage
Qiang Chen,Yichen Cai,Xiaoyu Zhu,Jing Wang,Feng Gao,Ming-feng Yang,Leilei Mao,Zong-yong Zhang,Bao-liang Sun +8 more
TL;DR: It is demonstrated that edaravone dexborneol confers neuroprotection and stabilizes long-term behavioral ability after SAH injury, possibly by suppressing 4-HNE-associated oxidative stress.
Inhibition of the pyroptosis-associated inflammasome pathway: The important potential mechanism of ginsenosides in ameliorating diabetes and its complications.
TL;DR: In this article , a review summarizes the subtypes of ginsenosides and their chemical characteristics, pharmacokinetics and side effects, the main pyroptosis-associated inflammasome pathways that have been discovered to date, and the potential mechanism of different subtypes in the treatment of DM and its complications (such as diabetic cardiomyopathy, diabetic nephropathy, diabetic liver injury, diabetic retinopathy, and diabetic ischemic stroke).
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Probiotics therapy show significant improvement in obesity and neurobehavioral disorders symptoms
Yichen Cai,Pan Liu,Xiaolan Zhou,J. Yuan,Qiu Chen +4 more
TL;DR: A review of studies on the effectiveness of probiotic interventions in reducing cognitive impairment, depression, and anxiety associated with obesity or a high-fat diet is presented in this article , where most of the probiotics studied have beneficial health effects on obesity-induced cognitive impairment and anxiety.
Administration of intramuscular AAV-BDNF and intranasal AAV-TrkB promotes neurological recovery via enhancing corticospinal synaptic connections in stroke rats
Jing Wang,Yichen Cai,Jing-yi Sun,Hualin Feng,Xiaoyu Zhu,Qian Chen,Feng Gao,Qing-bin Ni,Leilei Mao,Ming-feng Yang,Bao-liang Sun +10 more
TL;DR: In this article , the effects of combination therapy with adeno-associated virus (AAV) vectors carrying genes encoding BDNF or TrkB were evaluated in a permanent rat middle cerebral artery occlusion (MCAO) model.
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