6 Papers
12 Citations
Yi Wei is an academic researcher from Beijing University of Chinese Medicine. The author has contributed to research in topics: Signal transduction & Proinflammatory cytokine. The author has an hindex of 6, co-authored 6 publications.
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Papers
Chlorogenic acid induces apoptosis to inhibit inflammatory proliferation of IL-6-induced fibroblast-like synoviocytes through modulating the activation of JAK/STAT and NF-κB signaling pathways
Lixia Lou,Jingwei Zhou,Yujun Liu,Yi Wei,Jiuli Zhao,Jiagang Deng,Bin Dong,Lingqun Zhu,Aiming Wu,Yingxi Yang,Limin Chai +10 more
TL;DR: The present results indicated that CGA may have potential as a novel therapeutic agent for inhibiting inflammatory hyperplasia of the synovium through inducing synoviocyte apoptosis in patients with RA.
Chlorogenic acid and luteolin synergistically inhibit the proliferation of interleukin-1β-induced fibroblast-like synoviocytes through regulating the activation of NF-κB and JAK/STAT-signaling pathways.
TL;DR: The finding suggested that the combination of CGA and Lut may be a potential therapeutic treatment for the inflammatory proliferation of synoviocytes in patients with RA.
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Herbal formula Xian-Fang-Huo-Ming-Yin regulates differentiation of lymphocytes and production of pro-inflammatory cytokines in collagen-induced arthritis mice
Jinyu Li,Yi Wei,Xue Li,Dashuai Zhu,Bo Nie,Jingwei Zhou,Lixia Lou,Bin Dong,Aiming Wu,Yongzhe Che,Meng Chen,Lingqun Zhu,Mingwei Mu,Limin Chai +13 more
TL;DR: XFHM can regulate and maintain the immunologic balance of lymphocytic immunity and inhibit the production of pro-inflammatory cytokines, thus suppressing the pathological changes of RA, and may be used as an application of traditional medicine against RA in modern complementary and alternative therapeutics.
Chinese Herbal Formula, Modified Danggui Buxue Tang, Attenuates Apoptosis of Hematopoietic Stem Cells in Immune-Mediated Aplastic Anemia Mouse Model.
Jingwei Zhou,Xue Li,Peiying Deng,Yi Wei,Juan Liu,Meng Chen,Yamei Xu,Dongmei Zhang,Lingqun Zhu,Lixia Lou,Bin Dong,Qiushuo Jin,Limin Chai +12 more
TL;DR: DGBX can relieve the immune-mediated destruction of HSCs, repair hematopoietic failure, and recover the hematoplastic anemia function of H SCs in hematogenesis, and can be used in traditional medicine against AA as a complementary and alternative immunosuppressive therapeutic formula.
The herbal decoction modified Danggui Buxue Tang attenuates immune-mediated bone marrow failure by regulating the differentiation of T lymphocytes in an immune-induced aplastic anemia mouse model.
TL;DR: Results indicate that DGBX can regulate the differentiation of T lymphocytes, resulting in immunosuppressive and hematogenic functions on AA mice, and might be a good candidate for inclusion in a randomized study for AA with more data on the possible side effects and doses used in humans.