Yi Sui
Shenyang Medical College
34 Papers
38 Citations
Yi Sui is an academic researcher from Shenyang Medical College. The author has contributed to research in topics: Medicine & Stroke. The author has an hindex of 9, co-authored 27 publications. Previous affiliations of Yi Sui include Allen Institute for Brain Science & Florey Institute of Neuroscience and Mental Health.
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Papers
Micro-RNA-137 Inhibits Tau Hyperphosphorylation in Alzheimer's Disease and Targets the CACNA1C Gene in Transgenic Mice and Human Neuroblastoma SH-SY5Y Cells
TL;DR: In a transgenic mouse model of AD, miR-137 and expression of the CACNA1C gene inhibited the hyperphosphorylation of tau protein and regulated the expression of a calcium voltage-gated channel subunit of L-type calcium channel.
Association between Alzheimer's disease pathogenesis and early demyelination and oligodendrocyte dysfunction.
TL;DR: The findings indicate that the involvement of early demyelination at 3 months and the oligodendrocyte dysfunction at 6 months in APP/PS1 mice are in association with Alzheimer’s disease pathogenesis.
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Reduced proliferation in the adult mouse subventricular zone increases survival of olfactory bulb interneurons.
TL;DR: The number of OB interneurons following reduced SVZ proliferation is maintained through an increased survival of adult-born precursor cells, neuroblasts and interneURons.
Targeting CCR3 to Reduce Amyloid-β Production, Tau Hyperphosphorylation, and Synaptic Loss in a Mouse Model of Alzheimer’s Disease
TL;DR: The age-related increase in CCL11 may be a risk factor of AD, and antagonizing CCR3 may bring therapeutic benefits to AD.
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Female mice lacking cholecystokinin 1 receptors have compromised neurogenesis, and fewer dopaminergic cells in the olfactory bulb
Yi Sui,Rob Vermeulen,Rob Vermeulen,Tomas Hökfelt,Malcolm K. Horne,Malcolm K. Horne,Malcolm K. Horne,Davor Stanic,Davor Stanic,Davor Stanic +9 more
TL;DR: It is concluded that CCK, via CCK1Rs, is involved in regulating the generation of proliferating cells and neuroblasts in the adult female mouse brain, and mechanisms are in place to maintain steady neuronal populations in the OB and DG when the rate of proliferation is altered.