Yi Song
Northwest A&F University
3 Papers
5 Citations
Yi Song is an academic researcher from Northwest A&F University. The author has contributed to research in topics: Chemistry & Isothermal titration calorimetry. The author has an hindex of 1, co-authored 3 publications.
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Papers
The galloyl moiety enhances the inhibitory activity of catechins and theaflavins against α-glucosidase by increasing the polyphenol–enzyme binding interactions
TL;DR: The in vivo hypoglycemic effects of galloylated polyphenols suggest that the GM may be considered as a pharmaceutical fragment for the alleviation of type II diabetes symptoms through α-glucosidase inhibition.
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Caffeoyl substitution decreased the binding and inhibitory activity of quinic acid against α-amylase: The reason why chlorogenic acid is a relatively weak enzyme inhibitor.
TL;DR: Caffeoyl substitution decreased α-amylase inhibition of QA through reducing its binding affinity to the enzyme, indicating that change in α-Amylase spatial structure was related with enzyme residue sites involved in interactions with inhibitors, instead of with inhibition effect.
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Both Acidic pH Value and Binding Interactions of Tartaric Acid With α-Glucosidase Cause the Enzyme Inhibition: The Mechanism in α-Glucosidase Inhibition of Four Caffeic and Tartaric Acid Derivates
TL;DR: The inhibition mechanism of four caffeic and tartaric acid derivates against α-glucosidase was characterized by substrate depletion, fluorescence quenching, isothermal titration calorimetry (ITC) and molecular docking.