Yi Luan
New York University
9 Papers
39 Citations
Yi Luan is an academic researcher from New York University. The author has contributed to research in topics: ADAMTS & Cellular differentiation. The author has an hindex of 8, co-authored 8 publications. Previous affiliations of Yi Luan include Shandong University.
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Papers
Inhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulin
Yi Luan,Li Kong,D.R. Howell,Kirill Ilalov,Marc Fajardo,X.-H. Bai,P. E. Di Cesare,Mary B. Goldring,Steven B. Abramson,Chuan-ju Liu +9 more
TL;DR: The authors' observations demonstrate the importance of COMP degradation by ADAMTS-7 and ADAMts-12 in vivo and indicate that a(2)M represents the first endogenous inhibitor of ADAM TS-7- and ADamTS-12.
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ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein.
Chuan-ju Liu,Chuan-ju Liu,Wei Kong,Ke Xu,Yi Luan,Yi Luan,Kiril Ilalov,Bantoo Sehgal,Shuang Yu,Ronald D. Howell,Paul E. Di Cesare +10 more
TL;DR: Findings indicate that ADAMTS-12 is a new COMP-interacting and -degrading enzyme and thus may play an important role in the COMP degradation in the initiation and progression of arthritis.
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ADAMTS-7, a direct target of PTHrP, adversely regulates endochondral bone growth by associating with and inactivating GEP growth factor.
Xiaohui Bai,Dawei Wang,Dawei Wang,Li Kong,Yan Zhang,Yi Luan,Tatsuya Kobayashi,Henry M. Kronenberg,Xiuping Yu,Xiuping Yu,Chuan-ju Liu,Chuan-ju Liu +11 more
TL;DR: It is demonstrated that ADAMTS-7, a direct target of PTHrP signaling, negatively regulates endochondral bone formation by associating with and inactivating GEP chondrogenic growth factor.
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The Retinoblastoma Protein Is an Essential Mediator of Osteogenesis That Links the p204 Protein to the Cbfa1 Transcription Factor Thereby Increasing Its Activity
Yi Luan,Yi Luan,Xiuping Yu,Ke Xu,Bo Ding,Jin Yu,Yan Huang,Ning Yang,Peter Lengyel,Paul E. Di Cesare,Chuan-ju Liu,Chuan-ju Liu +11 more
TL;DR: It is established that suppression of p204 expression by an adenovirus construct encoding p204 antisense RNA inhibited osteoblast-specific gene activation by Cbfa1 in an osteogenesis assay involving the pluripotent C2C12 mesenchymal cell line.
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p204, a p200 family protein, as a multifunctional regulator of cell proliferation and differentiation.
TL;DR: This review concentrates on p204, a murine member of the p200 family, and its roles in regulating cell proliferation, cell and tissue differentiation and signaling by Ras proteins.
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