6 Papers
Yi Lu is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 1, co-authored 1 publications.
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Papers
The Role of CARD9 in Metabolic Diseases
Cheng Tian,Yali Tuo,Yi Lu,Chuan-Rui Xu,Ming Xiang +4 more
- 26 Apr 2020
TL;DR: This review summarizes CARD9 signaling pathway and the role of CARD9 in metabolic diseases and indicates that CARD9 is strongly associated with metabolic diseases, such as obesity, insulin resistance, atherosclerosis and so on.
Regenerating islet‐derived protein 3 gamma (Reg3g) ameliorates tacrolimus‐induced pancreatic β‐cell dysfunction in mice by restoring mitochondrial function
Senlin Li,Hongmin Zhou,Meng-Yang Xie,Zijun Zhang,Jing Gou,Jianru Yang,Cheng Tian,Kunpeng Ma,Cong-Yi Wang,Yi Lu,Qingwen Li,Wen Peng,Ming Xiang +12 more
TL;DR: In this article , the role of Reg3g in reversing tacrolimus-induced β-cell dysfunction and NODM in mice was investigated, and it was shown that regressing islet derived protein 3 gamma (Reg3g), a member of the pancreatic regenerative gene family, can improve type 1 diabetes.
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Cytochalasin Q exerts anti-melanoma effect by inhibiting creatine kinase B.
Yi Lu,Peng Zhang,Hongdan Chen,Qingyi Tong,Jia Wang,Qing Li,Cheng Tian,Jian Yang,Senlin Li,Zijun Zhang,H. Yuan,Ming Xiang +11 more
TL;DR: In this article , the anti-melanoma activity of CQ from Xylaria sp. DO1801, the endophytic fungi from the root of plant Damnacanthus officinarum, was investigated.
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CARD9 deficiency promotes pancreatic cancer growth by blocking dendritic cell maturation via SLC6A8-mediated creatine transport
Cheng Tian,Hui-Min Yuan,Yi Lu,H. He,Qing Li,Senlin Li,Jianru Yang,Meng-Chen Wang,Ruo-Fan Xu,Qian Liu,Ming Xiang +10 more
TL;DR: In this article , the expression of caspase-recruitment domain-containing protein 9 (CARD9), predominantly expressed in innate immune cells, was positively related to the prognosis of PC patients.
The combination of gemcitabine and ginsenoside Rh2 enhances the immune function of dendritic cells against pancreatic cancer via the CARD9-BCL10-MALT1 / NF-κB pathway.
Qing Li,Jialuo He,Senlin Li,Cheng Tian,Jian Yang,Hui-Min Yuan,Yi Lu,Paolo Fagone,Ferdinando Nicoletti,Ming Xiang +9 more
TL;DR: In this article , the authors showed that after GEM-Rh2 therapy, there was significantly greater tumor infiltration by dendritic cells (DCs), and that the activation of DCs may remodel the cold tumor immune microenvironment (TIME) and optimize GEM chemotherapy for future therapeutic use.