Biotechnological approaches for the production of natural colorants by Talaromyces/Penicillium: A review.

Azaphilones have continuously aroused considerable attention owing to their structural diversity and significant biological activities recently. This review attempts to give a comprehensive summary of recent progress on the isolation, identification, and biological activity, along with synthetic and biosynthetic studies of azaphilones reported from October 2012 to December 2019. Herein, a total of 252 compounds predominantly originated from 32 genera of fungi, such as Penicillium (20%) and Talaromyces (11%), were included in this research with citations of 105 references. Among these azaphilones, approximately half of them were found with various biological activities, of which over 40% displayed cytotoxic/anti-tumor effects. This review would shed light on the future development and research of azaphilones.

/pdf/recent-advances-in-the-chemistry-and-biology-of-azaphilones-5g6jq8fcso.pdf

Recent advances in the chemistry and biology of azaphilones

Newly reported alkaloids produced by marine-derived Penicillium species (covering 2014-2018).

Dibenzo-α-pyrones from the endophytic fungus Alternaria sp. Samif01: isolation, structure elucidation, and their antibacterial and antioxidant activities.

The present volume is the third in a trilogy that documents naturally occurring organohalogen compounds, bringing the total number-from fewer than 25 in 1968-to approximately 8000 compounds to date. Nearly all of these natural products contain chlorine or bromine, with a few containing iodine and, fewer still, fluorine. Produced by ubiquitous marine (algae, sponges, corals, bryozoa, nudibranchs, fungi, bacteria) and terrestrial organisms (plants, fungi, bacteria, insects, higher animals) and universal abiotic processes (volcanos, forest fires, geothermal events), organohalogens pervade the global ecosystem. Newly identified extraterrestrial sources are also documented. In addition to chemical structures, biological activity, biohalogenation, biodegradation, natural function, and future outlook are presented. 

Naturally Occurring Organohalogen Compounds-A Comprehensive Review.

Azaphilones isolated from an alga-derived fungus Penicillium sp. ZJ-27

Two new macrosporin dimers from the fungus Alternaria sp. XZSBG-1.

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Azaphilones isolated from an alga-derived fungus Penicillium sp. ZJ-27

Two new macrosporin dimers from the fungus Alternaria sp. XZSBG-1.