12 Papers
32 Citations
Yi Liao is an academic researcher from China Agricultural University. The author has contributed to research in topics: Mycobacterium bovis & Innate immune system. The author has an hindex of 6, co-authored 12 publications.
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Papers
Nilotinib: A Tyrosine Kinase Inhibitor Mediates Resistance to Intracellular Mycobacterium Via Regulating Autophagy.
Tariq Hussain,Deming Zhao,Syed Zahid Ali Shah,Syed Zahid Ali Shah,Naveed Sabir,Jie Wang,Yi Liao,Yinjuan Song,Haodi Dong,Mazhar Hussain Mangi,Jiamin Ni,Lifeng Yang,Xiangmei Zhou +12 more
TL;DR: The data showed that nilotinib regulates protective innate immune responses against intracellular mycobacterium, both in-vitro and in- vivo, and can be exploited as a novel therapeutic remedy for the control of M. bovis and MAP infections.
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MicroRNA-199a Inhibits Cellular Autophagy and Downregulates IFN-β Expression by Targeting TBK1 in Mycobacterium bovis Infected Cells.
Jie Wang,Tariq Hussain,Ruichao Yue,Yi Liao,Qiang Li,Jiao Yao,Yinjuan Song,Xin Sun,Nan Wang,Lei Xu,Srinand Sreevatsan,Deming Zhao,Xiangmei Zhou +12 more
TL;DR: It is demonstrated that, by targeting of TBK1, miR-199a modulates innate immune responses and promote the intracellular survival and growth of M. bovis.
Endoplasmic Reticulum Stress Induces Macrophages to Produce IL-1β During Mycobacterium bovis Infection via a Positive Feedback Loop Between Mitochondrial Damage and Inflammasome Activation
Yi Liao,Tariq Hussain,Chunfa Liu,Yongyong Cui,Jie Wang,Jiao Yao,Hehua Chen,Yinjuan Song,Naveed Sabir,Mazhar Hussain,Deming Zhao,Xiangmei Zhou +11 more
TL;DR: The data suggest that ERS induces macrophages to produce mature IL-1β during infection with virulent M. bovis through a positive feedback loop between mitochondrial damage and inflammasome activation.
Sodium Butyrate Abrogates the Growth and Pathogenesis of Mycobacterium bovis via Regulation of Cathelicidin (LL37) Expression and NF-κB Signaling.
Kai Zhang,Tariq Hussain,Tariq Hussain,Jie Wang,Mengying Li,Wenjia Wang,Xiaojing Ma,Yi Liao,Jiao Yao,Yinjuan Song,Zhengmin Liang,Xiangmei Zhou,Lihua Xu +12 more
TL;DR: The results suggest that NaB can be exploited as a therapeutic strategy for the control of M. bovis in animals and human beings.
Inhibition of type I interferon signaling abrogates early Mycobacterium bovis infection.
Jie Wang,Jie Wang,Tariq Hussain,Kai Zhang,Yi Liao,Jiao Yao,Yinjuan Song,Naveed Sabir,Guangyu Cheng,Haodi Dong,Miaoxuan Li,Jiamin Ni,Mazhar Hussain Mangi,Deming Zhao,Xiangmei Zhou +14 more
TL;DR: Results reveal that Type I IFN mediates a balance between M. bovis-mediated inflammatory reaction and host defense mechanism, which could be exploited as a therapeutic strategy against a large repertoire of inflammatory disorders including tuberculosis.