3 Papers
Yi Ding is an academic researcher from Allen Institute for Brain Science. The author has contributed to research in topics: Enhancer & Gene. The author has an hindex of 3, co-authored 3 publications.
Chat about Author
Papers
Functional enhancer elements drive subclass-selective expression from mouse to primate neocortex
John K. Mich,Lucas T. Graybuck,Hess Erik,Joseph T. Mahoney,Yoshiko Kojima,Yi Ding,Saroja Somasundaram,Jeremy A. Miller,Brian E. Kalmbach,Brian E. Kalmbach,Cristina Radaelli,Bryan B. Gore,Natalie Weed,Victoria Omstead,Yemeserach Bishaw,Nadiya V. Shapovalova,Refugio A. Martinez,Olivia Fong,Shenqin Yao,Marty Mortrud,Peter Chong,Luke Loftus,Darren Bertagnolli,Jeff Goldy,Tamara Casper,Nick Dee,Ximena Opitz-Araya,Ali Cetin,Kimberly A. Smith,Ryder P. Gwinn,Charles Cobbs,Andrew L. Ko,Andrew L. Ko,Jeffrey G. Ojemann,Jeffrey G. Ojemann,C. Dirk Keene,Daniel L. Silbergeld,Susan M. Sunkin,Viviana Gradinaru,Gregory D. Horwitz,Hongkui Zeng,Bosiljka Tasic,Ed S. Lein,Ed S. Lein,Ed S. Lein,Jonathan T. Ting,Jonathan T. Ting,Boaz P. Levi +47 more
TL;DR: In this paper, comparative open chromatin analysis was used to identify thousands of human-neocortical-subclass-specific putative enhancers from across the genome to control gene expression in adeno-associated virus (AAV) vectors.
142
Functional enhancer elements drive subclass-selective expression from mouse to primate neocortex
John K. Mich,Lucas T. Graybuck,Hess Erik,Joseph T. Mahoney,Yoshiko Kojima,Yi Ding,Saroja Somasundaram,Jeremy A. Miller,Natalie Weed,Victoria Omstead,Yemeserach Bishaw,Nadiya V. Shapovalova,Refugio A. Martinez,Olivia Fong,Shenqin Yao,Marty Mortrud,Peter Chong,Luke Loftus,Darren Bertagnolli,Jeff Goldy,Tamara Casper,Nick Dee,Ximena Opitz-Araya,Ali Cetin,Kimberly A. Smith,Ryder P. Gwinn,Charles Cobbs,Andrew L. Ko,Jeffrey G. Ojemann,Jeffrey G. Ojemann,C. Dirk Keene,Daniel L. Silbergeld,Susan M. Sunkin,Viviana Gradinaru,Gregory D. Horwitz,Hongkui Zeng,Bosiljka Tasic,Ed S. Lein,Jonathan T. Ting,Boaz P. Levi +39 more
TL;DR: Comparative epigenetics is used to identify thousands of human neuronal subclass-specific putative enhancers to regulate viral tools, and 34% of these were conserved in mouse, and could yield brain-wide specificity greater than the most selective marker genes.
74
Functional Enhancer Elements Drive Subclass-Selective Expression from Mouse to Primate Neocortex
John K. Mich,Lucas T. Graybuck,Hess Erik,Joseph T. Mahoney,Yoshiko Kojima,Yi Ding,Saroja Somasundaram,Jeremy A. Miller,Natalie Weed,Victoria Omstead,Yemeserach Bishaw,Nadiya V. Shapovalova,Refugio A. Martinez,Olivia Fong,Shenqin Yao,Marty Mortrud,Peter Chong,Luke Loftus,Darren Bertagnolli,Jeff Goldy,Tamara Casper,Nick Dee,Ximena Opitz-Araya,Ali Cetin,Kimberly A. Smith,Ryder P. Gwinn,Charles Cobbs,Andrew L. Ko,Jeffrey G. Ojemann,Jeffrey G. Ojemann,C. Dirk Keene,Daniel L. Silbergeld,Susan M. Sunkin,Viviana Gradinaru,Gregory D. Horwitz,Hongkui Zeng,Bosiljka Tasic,Ed S. Lein,Jonathan T. Ting,Boaz P. Levi +39 more
TL;DR: Comparative epigenetics is used to identify thousands of human neuronal subclass-specific putative enhancers to regulate viral tools, and 34% of these were conserved in mouse, and could yield brain-wide specificity greater than the most selective marker genes.