Yi Chen
Wuhan University
11 Papers
57 Citations
Yi Chen is an academic researcher from Wuhan University. The author has contributed to research in topics: RNA & Rolling circle replication. The author has an hindex of 6, co-authored 11 publications.
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Papers
Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein
Tianlu Wang,Tingting Hong,Yue Huang,Haomiao Su,Fan Wu,Yi Chen,Lai Wei,Wei Huang,Xiaoluan Hua,Yu Xia,Jinglei Xu,Jianhua Gan,Bi-Feng Yuan,Yu-Qi Feng,Xiao-Lian Zhang,Cai-Guang Yang,Xiang Zhou +16 more
TL;DR: It is identified that fluorescein derivatives can selectively inhibit FTO demethylation and these inhibitors can also be applied to the direct labeling and enrichment of FTO protein combined with photoaffinity labeling assay.
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N1-Methyladenosine detection with CRISPR-Cas13a/C2c2.
TL;DR: CRISPR Cas13a provided a robust, simple and fluorescence-based method for m 1A detection and dynamic m1A demethylation analysis of 28S rRNA.
A highly efficient fluorescence-based switch-on detection method of 5-formyluracil in DNA
Chaoxing Liu,Yuqi Chen,Yafen Wang,Fan Wu,Xiong Zhang,Wei Yang,Jiaqi Wang,Yi Chen,Zhiyong He,Guangrong Zou,Shaoru Wang,Xiang Zhou +11 more
TL;DR: The innoxiousness, convenience, and cost-efficiency of the 5-formyluracil phosphoramidite synthetic routine would promote the understanding of the epigenetic role of this natural thymidine modification.
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An aptamer-based ligation-triggered rolling circle amplification strategy for ATP detection and imaging in situ
TL;DR: This work has developed an aptamer-based ligation-triggered rolling circle amplification strategy for ATP detection that could be used to detect ATP in complex biological matrix, cell lysates, and the detection limit was as low as five cells.
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Luminescence Sensing for Qualitative and Quantitative Detection of 5-Methylcytosine.
Yushu Yuan,Tingting Hong,Yi Chen,Yafen Wang,Xueping Qiu,Fang Zheng,Xiaocheng Weng,Xiang Zhou +7 more
TL;DR: A luminescence sensing strategy based on bisulfite treatment, asymmetric polymerase chain reaction (PCR), and adenosine triphosphate (ATP)-releasing nucleotide is proposed and can be successfully employed to determine the methylation status of three hepatocellular carcinomas (HCC) related genes in clinical tissues.
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