Ye Wang
University of Alberta
19 Papers
141 Citations
Ye Wang is an academic researcher from University of Alberta. The author has contributed to research in topics: Vaccenic acid & Postprandial. The author has an hindex of 13, co-authored 19 publications.
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Papers
Trans-11 Vaccenic Acid Dietary Supplementation Induces Hypolipidemic Effects in JCR:LA-cp Rats
Ye Wang,Jing Lu,Megan R. Ruth,Susan Goruk,Martin J. T. Reaney,David R. Glimm,Donna F. Vine,Catherine J. Field,Spencer D. Proctor +8 more
TL;DR: In conclusion, short-term dietary supplementation of 1.5% VA did not result in any detrimental metabolic effects in JCR:LA-cp rats, and dietary VA had substantial hypo-triglyceridemic effects, suggesting a new bioactivity of this fatty acid that is typically found in ruminant-derived food products.
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The role of ruminant trans fat as a potential nutraceutical in the prevention of cardiovascular disease
TL;DR: This review discusses the most recent findings from human and animal intervention studies on the health implications and potential mechanisms of two major rTFA in their purified form as well as in the format of dairy fat with regard to the development of cardiovascular diseases, with the aim of assessing the potential of developing rT FA as novel components for functional foods.
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Trans-11 Vaccenic Acid Reduces Hepatic Lipogenesis and Chylomicron Secretion in JCR:
Ye Wang,Miriam Jacome-Sosa,Megan R. Ruth,Susan Goruk,Martin J. T. Reaney,David R. Glimm,David C. Wright,Donna F. Vine,Catherine J. Field,Spencer D. Proctor +9 more
- 01 Jan 2009
TL;DR: Chronic VA supplementation significantly improved dyslipidemia in both the food-deprived and postprandial state in JCR:LA-cp rats, and may be attributed to a reduction in both intestinal CM and hepatic de novo lipogenesis pathways.
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Increased hypolipidemic benefits of cis -9, trans -11 conjugated linoleic acid in combination with trans -11 vaccenic acid in a rodent model of the metabolic syndrome, the JCR:LA -cp rat
Miriam Jacome-Sosa,Jing Lu,Ye Wang,Megan R. Ruth,David C. Wright,Martin J. T. Reaney,Jianheng Shen,Catherine J. Field,Donna F. Vine,Spencer D. Proctor +9 more
TL;DR: It is demonstrated that the hypolipidemic effects of chronic cis-9, trans-11 CLA supplementation on circulating dyslipidemia and hepatic steatosis are enhanced by the addition of VA in the JCR:LA-cp rat.
The intestinal bioavailability of vaccenic acid and activation of peroxisome proliferator-activated receptor-α and -γ in a rodent model of dyslipidemia and the metabolic syndrome.
Ye Wang,Maria M. Jacome-Sosa,Megan R. Ruth,Yan Lu,Jianheng Shen,Martin J. T. Reaney,Shannon L. Scott,Michael E. R. Dugan,Hope D. Anderson,Catherine J. Field,Spencer D. Proctor,Donna F. Vine +11 more
TL;DR: The activation of PPar-α- and PPAR-γ-dependent pathways provides a mechanistic explanation of how VA improves blood lipids and related metabolic disorders during conditions of hyperlipidemia.
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