Yazmín Macotela
National Autonomous University of Mexico
55 Papers
178 Citations
Yazmín Macotela is an academic researcher from National Autonomous University of Mexico. The author has contributed to research in topics: Prolactin & Adipose tissue. The author has an hindex of 24, co-authored 38 publications. Previous affiliations of Yazmín Macotela include Federal University of São Paulo & Max Planck Society.
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Papers
Sex and Depot Differences in Adipocyte Insulin Sensitivity and Glucose Metabolism
TL;DR: There are major sex differences in insulin sensitivity in adipose tissue, particularly in the intra-abdominal depot, that are regulated by physiological levels of sex steroids.
397
Intrinsic Differences in Adipocyte Precursor Cells From Different White Fat Depots
Yazmín Macotela,Brice Emanuelli,Marcelo A. Mori,Stephane Gesta,Tim J. Schulz,Yu-Hua Tseng,C. Ronald Kahn +6 more
TL;DR: It is demonstrated that adipocyte precursor cells (APCs) isolated from visceral and subcutaneous white adipose depots of mice have distinct patterns of gene expression, differentiation potential, and response to environmental and genetic influences.
Adipose-Specific Deletion of TFAM Increases Mitochondrial Oxidation and Protects Mice against Obesity and Insulin Resistance
Cecile Vernochet,Arnaud Mourier,Olivier Bezy,Yazmín Macotela,Jeremie Boucher,Matthew J. Rardin,Ding An,Kevin Y. Lee,Olga Ilkayeva,Cristina M. Zingaretti,Brice Emanuelli,Graham Smyth,Saverio Cinti,Christopher B. Newgard,Bradford W. Gibson,Nils-Göran Larsson,C. Ronald Kahn +16 more
TL;DR: F-TFKO mice exhibit higher energy expenditure and are protected from age- and diet-induced obesity, insulin resistance, and hepatosteatosis, suggesting that regulation of adipose tissue mitochondria may be a potential therapeutic target for the treatment of obesity.
254
ASC-1, PAT2, and P2RX5 are cell surface markers for white, beige, and brown adipocytes
Siegfried Ussar,Kevin Y. Lee,Simon N. Dankel,Simon N. Dankel,Simon N. Dankel,Jeremie Boucher,Max-Felix Haering,André Kleinridders,Thomas Thomou,Ruidan Xue,Yazmín Macotela,Aaron M. Cypess,Yu-Hua Tseng,Gunnar Mellgren,Gunnar Mellgren,C. Ronald Kahn +15 more
TL;DR: Three new surface markers of white, beige, and brown fat cells are identified using a combination of in silico, in vitro, and in vivo methods to identify and target white and brown/beige adipocytes for therapeutic purposes.
Impaired Thermogenesis and Adipose Tissue Development in Mice with Fat-Specific Disruption of Insulin and IGF-1 Signalling
Jeremie Boucher,Marcelo A. Mori,Marcelo A. Mori,Kevin Y. Lee,Graham Smyth,Graham Smyth,Chong Wee Liew,Yazmín Macotela,Yazmín Macotela,Michael Rourk,Matthias Blüher,Steven Russell,C. Ronald Kahn +12 more
TL;DR: Mice created with a double tissue-specific knockout of insulin and IGF-1 receptors to eliminate all insulin/IGF-1 signaling in fat were completely resistant to high fat diet (HFD) induced obesity and age- and HFD-induced glucose intolerance.