Yazhen Wang
Sichuan University
3 Papers
Yazhen Wang is an academic researcher from Sichuan University. The author has contributed to research in topics: Protein Corona & Internalization. The author has an hindex of 1, co-authored 3 publications.
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Papers
The protein corona hampers the transcytosis of transferrin-modified nanoparticles through blood-brain barrier and attenuates their targeting ability to brain tumor.
Wei Xiao,Yazhen Wang,Huilin Zhang,Yuwei Liu,Rou Xie,Xueqin He,Yang Zhou,Luqing Liang,Huile Gao +8 more
TL;DR: In this article, transferrin (Tf) was coupled with nanoparticles to evaluate BBB transcytosis and brain tumor targeting ability, and different impacts of the in vitro and in vivo protein corona on receptor targeting, lysosomal escape, and BBBtranscytotic processes were found.
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Unmasking CSF protein corona: Effect on targeting capacity of nanoparticles.
Yazhen Wang,Huilin Zhang,Wei Xiao,Yuwei Liu,Yang Zhou,Xueqin He,Xue Xia,Tao Gong,Ling Wang,Huile Gao +9 more
TL;DR: In this paper, two types of polystyrene NPs, including PEGylated polystyrin NPs (PN) and transferrin (Tf)-modified PN (PT), were used to obtain protein corona-coated NPs by incubating with CSF in vivo and in vitro.
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Unraveling the Effect of Breast Cancer Patients' Plasma on the Targeting Ability of Folic Acid-Modified Chitosan Nanoparticles.
Mahdieh Nemati,Farhad Bani,Tina Sepasi,Reza Eghdam Zamiri,Yousef Rasmi,Houman Kahroba,Reza Rahbarghazi,Reza Rahbarghazi,Mohammed Reza Sadeghi,Yazhen Wang,Amir Zarebkohan,Huile Gao +11 more
TL;DR: In this article, the formation of protein corona (PC) around nanoparticles (NPs) has been reported inside biological conditions, which can alter delivery capacity toward the targeted tissues.